Cardiovasc Imaging Asia.  2018 Apr;2(2):38-48. 10.22468/cvia.2018.00031.

Dynamic CT Perfusion Imaging: State of the Art

• Kitagawa K
• Goto Y
• Nakamura S
• Takafuji M
• Hamdy A
• Ishida M
• Sakuma H

• KMID: 2524862
• DOI: http://doi.org/10.22468/cvia.2018.00031

Abstract

Recent advances in computed tomography (CT) technology have enabled stress dynamic CT perfusion (CTP) imaging of the entire myocardium to be performed with high temporal resolution and reasonable radiation dose. The most important advantage of dynamic CTP is the feasibility of complete quantification of myocardial perfusion in mL/min/g. Although high diagnostic values have been reported for the detection of myocardial ischemia, standardization of acquisition method, mathematical modeling and interpretation, as well as further evaluation of its accuracy, clinical role, and cost effectiveness are required before its routine clinical implementation. The current review focuses on the state-of-the-art of dynamic CTP and outlines its current status and future directions as a new technology for the physiologic assessment of coronary artery disease.

Keyword

Multidetector computed tomography; Myocardial perfusion imaging; Coronary artery disease