J Korean Acad Oral Health.  2021 Dec;45(4):184-191. 10.11149/jkaoh.2021.45.4.184.

A study on the oral environment improvement effect of centella asiaticca extract and dentifrice containing potassium nitrate and potassium glyciric acid

Affiliations
  • 1Departments of 1 Oral Health and 2 Dental Hygiene, College of Health Science, Dankook University, Cheon, Korea
  • 2Departments of 1 Oral Health and 2 Dental Hygiene, College of Health Science, Dankook University, Cheon, Korea
  • 3Department of Preventive Dentistry, College of Dentistry, Dankook University, Cheon, Korea
  • 4HBD Division, Amorepacific R&D Center, Yongin, Korea
  • 5Department of Dental Hygiene, Gumi University, Gumi, Korea
  • 6Department of Dental Hygiene, Gangneung Yeongdong College, Gangneung, Korea

Abstract


Objectives
This study aimed to evaluate the effect of detergents containing a centella quantitative extract and dipotassium glycyrrhizinate and potassium nitrate on patient hygiene performance index, gingivitis index, gingival bleeding index, EPT, and halitosis.
Methods
A parallel comparison, randomized, double-blind, controlled trial was conducted for 8 weeks with 60 adult men and women as participants.
Results
According to the PMA index, gingival index of Talbott, gingival hemorrhage index, Turesky’s plaque index, and bad breath measurement, there was a statistically significant difference between the experimental group and the control group after 4 weeks (P<0.05).
Conclusions
It was confirmed that the bad breath reduction effect, gingival bleeding improvement effect, gingivitis inflammation effect, removal of the gingival microbial membrane, and syringin can be expected to relieve symptoms.

Keyword

Centella asiaticca; Dentifrice; Glyciric acid; Oral; Potassium nitrate

Reference

References

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