Infect Chemother.
2021 Dec;53(4):786-791. 10.3947/ic.2021.0077.
Clinical and Laboratory Factors Associated with Symptom Development in Asymptomatic COVID-19 Patients at the Time of Diagnosis
- Oh HS
1 - Kim JH2
- Woo ML3
- Kim JY4
- Park CH5
- Won H6
- Lim S7
- Jeong H8
- Ham SY8
- Kim EJ9
- Sheen S10
- Kang YM11
- Yoon D1
- Lee SY12
- Song KH8
- Affiliations
-
- 1Department of Internal Medicine, Armed Forces Capital Hospital, Seongnam, Korea
- 2Department of Surgery, Gyeonggi Provincial Medical Center, Uijeongbu Hospital, Uijeongbu, Korea
- 3Department of Internal Medicine, Gyeonggi Provincial Medical Center, Uijeongbu Hospital, Uijeongbu, Korea
- 4Division of Infectious Disease, Department of Medicine, Seongnam Citizens Medical Center, Seongnam, Korea
- 5Department of Internal Medicine, Gyeonggi Provincial Medical Center, Icheon Hospital, Icheon, Korea
- 6Department of Internal Medicine, Gyeonggi Provincial Medical Center, Pocheon Hospital, Pocheon, Korea
- 7Department of Internal Medicine, Gyeonggi Provincial Medical Center, Ansung Hospital, Anseong, Korea
- 8Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University, College of Medicine, Seongnam, Korea
- 9Department of Infectious Disease, Ajou University, School of Medicine, Suwon, Korea
- 10Department of Pulmonary Critical Care Medicine, Ajou University, School of Medicine, Suwon, Korea
- 11Division of Infectious Disease, Department of Internal Medicine, Myongji Hospital, Goyang, Korea
- 12Department of Emergency Medicine, Gyeonggi Provincial Medical Center, Ansung Hospital, Anseong, Korea
- KMID: 2524072
- DOI: http://doi.org/10.3947/ic.2021.0077
Abstract
- In preparation for the surge of coronavirus disease 2019 (COVID-19), it is crucial to allocate medical resources efficiently for distinguishing people who remain asymptomatic until the end of the disease. Between January 27, 2020, and April 21, 2020, 517 COVID-19 cases from 13 healthcare facilities in Gyeonggi province, Korea, were identified out of which the epidemiologic and clinical information of 66 asymptomatic patients at the time of diagnosis were analyzed retrospectively. An exposure-diagnosis interval within 7 days and abnormal aspartate aminotransferase levels were identified as characteristic symptom development in asymptomatic COVID-19 patients. If asymptomatic patients without these characteristics at the time of diagnosis could be differentiated early, more medical resources could be secured for mild or moderate cases in this COVID-19 surge.
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