Korean J Pain.  2021 Oct;34(4):487-500. 10.3344/kjp.2021.34.4.487.

Erector spinae plane block for spinal surgery: a systematic review and meta-analysis

Affiliations
  • 1Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China
  • 2Department of Infection Control, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China
  • 3Department of Anesthesiology, Sichuan Cancer Center, Sichuan Cancer Hospital & Institute, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China

Abstract

Background
Although the erector spinae plane block has been used in various truncal surgical procedures, its clinical benefits in patients undergoing spinal surgery remain controversial. The aim of this meta-analysis was to evaluate the clinical benefits of erector spinae plane block in patients undergoing spinal surgery.
Methods
We searched the Cochrane Library, PubMed, EMBASE, and China National Knowledge Infrastructure for randomized controlled trials comparing the erector spinae plane block with a nonblocked control for spinal surgery.
Results
Twelve studies encompassing 696 subjects were included in our systematic review and meta-analysis. We found that the erector spinae plane block decreased postoperative pain scores and opioid consumption in the postoperative and intraoperative periods. Moreover, it prolonged the time to the first rescue analgesic, reduced the number of patients who required rescue analgesia, and lowered the incidence of postoperative nausea and vomiting. However, it did not exhibit efficacy in decreasing the incidence of urinary retention and itching or shortening the length of hospital stays, or the time to first ambulation.
Conclusions
Erector spinae plane block improves analgesic efficacy among patients undergoing spinal surgery compared with nonblocked controls; however, there is insufficient evidence regarding the benefits of erector spinae plane block for rapid recovery.

Keyword

Analgesia; Analgesics; Opioid; Diskectomy; Enhanced Recovery After Surgery; Erector Spinae Plane Block; Laminectomy; Meta-Analysis; Nerve Block; Neurosurgical Procedures; Pain; Postoperative; Postoperative Nausea and Vomiting; Randomized Controlled Trial

Figure

  • Fig. 1 Study flow diagram.

  • Fig. 2 Risk of bias for each item according to RoB 2 [11].

  • Fig. 3 Summary plot of quality assessment of each study included according to RoB 2 [11].

  • Fig. 4 Funnel plot of 24- and 48-hour cumulative postoperative intravenous morphine equivalent consumption in the erector spinae plane block group versus the control group. SE: standard error, MD: mean difference.

  • Fig. 5 Forest plot of 24-hour and 48-hour cumulative postoperative intravenous morphine equivalent consumption (mg). ESPB: erector spinae plane block, SD: standard deviation, IV: inverse variance, CI: confidence interval, df: degree of freedom.

  • Fig. 6 Forest plot of pain score at rest at 0, 2, 4, 8, 12, 24, and 48 hours. ESPB: erector spinae plane block, SD: standard deviation, IV: inverse variance, CI: confidence interval, df: degree of freedom.

  • Fig. 7 Forest plot of pain score at movement at 0, 2, 4, 8, 12, 24, and 48 hours. ESPB: erector spinae plane block, SD: standard deviation, IV: inverse variance, CI: confidence interval, df: degree of freedom.

  • Fig. 8 Forest plot of overall pain score at 0, 2, 4, 6, 8, 12, 24, and 48 hours. ESPB: erector spinae plane block, SD: standard deviation, IV: inverse variance, CI: confidence interval, df: degree of freedom.


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Reference

1. Bajwa SJ, Haldar R. 2015; Pain management following spinal surgeries: an appraisal of the available options. J Craniovertebr Junction Spine. 6:105–10. DOI: 10.4103/0974-8237.161589. PMID: 26288544. PMCID: PMC4530508.
Article
2. Kurd MF, Kreitz T, Schroeder G, Vaccaro AR. 2017; The role of multimodal analgesia in spine surgery. J Am Acad Orthop Surg. 25:260–8. DOI: 10.5435/JAAOS-D-16-00049. PMID: 28291143.
Article
3. Cohen BE, Hartman MB, Wade JT, Miller JS, Gilbert R, Chapman TM. 1997; Postoperative pain control after lumbar spine fusion. Patient-controlled analgesia versus continuous epidural analgesia. Spine (Phila Pa 1976). 22:1892–6. DOI: 10.1097/00007632-199708150-00016. PMID: 9280026.
4. Mergeay M, Verster A, Van Aken D, Vercauteren M. 2015; Regional versus general anesthesia for spine surgery. A comprehensive review. Acta Anaesthesiol Belg. 66:1–9. PMID: 26103736.
5. Forero M, Adhikary SD, Lopez H, Tsui C, Chin KJ. 2016; The erector spinae plane block: a novel analgesic technique in thoracic neuropathic pain. Reg Anesth Pain Med. 41:621–7. DOI: 10.1097/AAP.0000000000000451. PMID: 27501016.
6. Tulgar S, Ahiskalioglu A, De Cassai A, Gurkan Y. 2019; Efficacy of bilateral erector spinae plane block in the management of pain: current insights. J Pain Res. 12:2597–613. DOI: 10.2147/JPR.S182128. PMID: 31695476. PMCID: PMC6717717.
7. Qiu Y, Zhang TJ, Hua Z. 2020; Erector spinae plane block for lumbar spinal surgery: a systematic review. J Pain Res. 13:1611–9. DOI: 10.2147/JPR.S256205. PMID: 32669870. PMCID: PMC7335845.
8. Moher D, Shamseer L, Clarke M, Ghersi D, Liberati A, Petticrew M, et al. 2015; Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev. 4:1. DOI: 10.1186/2046-4053-4-1. PMID: 25554246. PMCID: PMC4320440.
Article
9. Swarm RA, Paice JA, Anghelescu DL, Are M, Bruce JY, Buga S, et al. 2019; Adult cancer pain, version 3.2019, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw. 17:977–1007. DOI: 10.6004/jnccn.2019.0038. PMID: 31390582.
Article
10. Wan X, Wang W, Liu J, Tong T. 2014; Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range. BMC Med Res Methodol. 14:135. DOI: 10.1186/1471-2288-14-135. PMID: 25524443. PMCID: PMC4383202.
Article
11. Sterne JAC, Savović J, Page MJ, Elbers RG, Blencowe NS, Boutron I, et al. 2019; RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 366:l4898. DOI: 10.1136/bmj.l4898. PMID: 31462531.
Article
12. Balshem H, Helfand M, Schünemann HJ, Oxman AD, Kunz R, Brozek J, et al. 2011; GRADE guidelines: 3. Rating the quality of evidence. J Clin Epidemiol. 64:401–6. DOI: 10.1016/j.jclinepi.2010.07.015. PMID: 21208779.
Article
13. Ciftci B, Ekinci M, Celik EC, Yayik AM, Aydin ME, Ahiskalioglu A. 2020; Ultrasound-guided erector spinae plane block versus modified-thoracolumbar interfascial plane block for lumbar discectomy surgery: a randomized, controlled study. World Neurosurg. 144:e849–55. DOI: 10.1016/j.wneu.2020.09.077. PMID: 32956890.
Article
14. Eskin MB, Ceylan A, Özhan MÖ, Atik B. 2020; Ultrasound-guided erector spinae block versus mid-transverse process to pleura block for postoperative analgesia in lumbar spinal surgery. Anaesthesist. 69:742–50. DOI: 10.1007/s00101-020-00848-w. PMID: 32955601.
Article
15. Singh S, Choudhary NK, Lalin D, Verma VK. 2020; Bilateral ultrasound-guided erector spinae plane block for postoperative analgesia in lumbar spine surgery: a randomized control trial. J Neurosurg Anesthesiol. 32:330–4. DOI: 10.1097/ANA.0000000000000603. PMID: 31033625.
Article
16. Yayik AM, Cesur S, Ozturk F, Ahiskalioglu A, Ay AN, Celik EC, et al. 2019; Postoperative analgesic efficacy of the ultrasound-guided erector spinae plane block in patients undergoing lumbar spinal decompression surgery: a randomized controlled study. World Neurosurg. 126:e779–85. DOI: 10.1016/j.wneu.2019.02.149. PMID: 30853517.
Article
17. Yeşiltaş S, Abdallah A, Uysal Ö, Yilmaz S, Çinar İ, Karaaslan K. 2021; The efficacy of intraoperative freehand erector spinae plane block in lumbar spondylolisthesis: a randomized controlled study. Spine (Phila Pa 1976). 46:E902–10. DOI: 10.1097/BRS.0000000000003966. PMID: 33496536.
18. Yu Y, Wang M, Ying H, Ding J, Wang H, Wang Y. 2021; The analgesic efficacy of erector spinae plane blocks in patients undergoing posterior lumbar spinal surgery for lumbar fracture. World Neurosurg. 147:e1–7. DOI: 10.1016/j.wneu.2020.10.175. PMID: 33340727.
Article
19. Zhang Q, Wu Y, Ren F, Zhang X, Feng Y. 2021; Bilateral ultrasound-guided erector spinae plane block in patients undergoing lumbar spinal fusion: a randomized controlled trial. J Clin Anesth. 68:110090. DOI: 10.1016/j.jclinane.2020.110090. PMID: 33096517.
Article
20. Zhang TJ, Zhang JJ, Qu ZY, Zhang HY, Qiu Y, Hua Z. 2020; Bilateral erector spinae plane blocks for open posterior lumbar surgery. J Pain Res. 13:709–17. DOI: 10.2147/JPR.S248171. PMID: 32308470. PMCID: PMC7148416.
21. Liu T, Hua L, Wan L. 2019; Comparison of ultrasound-guided erector spinae plane block and retrolaminal block combined with general anesthesia for patients undergoing vertebral surgery. J Clin Anaesthesiol. 35:289–93. Chinese. https://caod.oriprobe.com/articles/56193427/Comparison_of_ultrasound_guided_erector_spinae_pla.htm.
22. Wang W, Liu Y, Zhang Y. 2018; Ultrasound-guided erector spine block as an adjuvant to general anesthesia and postoperative analgesia in patients undergoing lumbar spine surgery. J Clin Anaesthesiol. 34:1172–5. Chinese. https://caod.oriprobe.com/articles/55572781/Ultrasound_guided_erector_spine_block_as_an_adjuva.htm.
23. Wu Z, Xue F, Wang Z, Yang L, Chen X, Yao S. 2019; Analgesic efficacy of ultrasound-guided bilateral erector spinae plane block in patients undergoing posterior lumbar interbody fusion. J Clin Anaesthesiol. 35:842–5. Chinese. http://www.lcmzxzz.com/ch/reader/view_abstract.aspx?flag=1&file_no=201909002&journal_id=lcmzxzz.
24. Yu Q, Guo X. 2018; Ropivacaine erector spinae plane block assisting general anesthesia in lumbar spine surgery of 30 cases. Her Med. 37:63–6. Chinese. http://wprim.whocc.org.cn/admin/article/articleDetail?WPRIMID=665252&articleId=665252.
25. Huang W, Wang W, Xie W, Chen Z, Liu Y. 2020; Erector spinae plane block for postoperative analgesia in breast and thoracic surgery: a systematic review and meta-analysis. J Clin Anesth. 66:109900. DOI: 10.1016/j.jclinane.2020.109900. PMID: 32502778.
Article
26. Hong B, Bang S, Chung W, Yoo S, Chung J, Kim S. 2019; Multimodal analgesia with multiple intermittent doses of erector spinae plane block through a catheter after total mastectomy: a retrospective observational study. Korean J Pain. 32:206–14. DOI: 10.3344/kjp.2019.32.3.206. PMID: 31257829. PMCID: PMC6615445.
Article
27. Huang J, Liu JC. 2020; Ultrasound-guided erector spinae plane block for postoperative analgesia: a meta-analysis of randomized controlled trials. BMC Anesthesiol. 20:83. DOI: 10.1186/s12871-020-00999-8. PMID: 32290814. PMCID: PMC7155251.
Article
28. Hussain N, Brull R, Noble J, Weaver T, Essandoh M, McCartney CJ, et al. 2021; Statistically significant but clinically unimportant: a systematic review and meta-analysis of the analgesic benefits of erector spinae plane block following breast cancer surgery. Reg Anesth Pain Med. 46:3–12. DOI: 10.1136/rapm-2020-101917. PMID: 33168651.
Article
29. Kendall MC, Alves L, Traill LL, De Oliveira GS. 2020; The effect of ultrasound-guided erector spinae plane block on postsurgical pain: a meta-analysis of randomized controlled trials. BMC Anesthesiol. 20:99. DOI: 10.1186/s12871-020-01016-8. PMID: 32357842. PMCID: PMC7195766.
Article
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