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Reducing pain and opioid consumption after body contouring of the breast by application of a perioperative nerve block: a systematic review

Asserson DB, Sahar DE

Background Pain in the postoperative body contouring patient has traditionally been managed with narcotic medication. In an effort to minimize side effects and prevent addiction, plastic surgeons are searching for...
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A meta-analysis on advantages of peripheral nerve block post-total knee arthroplasty

You D, Qin L, Li K, Li D, Zhao G, Li L

Background: Postoperative pain management is crucial for patients undergoing total knee arthroplasty (TKA). There have been many recent clinical trials on post-TKA peripheral nerve block; however, they have reported inconsistent...
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The Effect of Patient-controlled Intravenous Analgesia (PCIA) on Postoperative Delirium in Patients with Liver Transplantation: a Propensity Score Matching Analysis

Son HJ, Jeong U, Choi K, Park JY, Choi EJ, Ri HS, Lee TB, Choi BH, Choi YJ

Objectives: Postoperative opioid use and pain are related to postoperative delirium. This study aims to compare the incidence of delirium in patients with and without patient-controlled intravenous analgesia (PCIA) among...
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Microscopic features of the rat adrenal gland associated with chronic codeine phosphate administration

Ongidi IH, Abdulsalaam FY, Amuti TM, Kaisha WO, Awori KO, Pulei AN

Codeine is an opioid analgesic and antitussive that has been widely abused. Some adverse effects noted with its abuse include adrenocortical insufficiency and activation of the hypothalamic-pituitary-adrenal axis. The structural...
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Effect of Opioids on All-cause Mortality and Sustained Opioid Use in Elderly Patients with Hip Fracture: a Korea Nationwide Cohort Study

Yoo JI, Jang SY, Cha Y, Park CH, Kim JT, Oh S, Choy W

Background: The purpose of our study was to assess the use of opioids before and after hip fracture in elderly patients in order to determine the effect of opioid use...
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Recent Trends in Opioid Prescription in Cancer Patients in Korea

Yoon J, Kim HS, Lee JW, Kim J, Kang HT

Background: This study aimed to estimate the trends in opioid prescriptions for pain control in patients with and without cancer between 2002 and 2015. Methods: This retrospective study was based on...
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Intravenous patient-controlled analgesia hydromorphone combined with pregabalin for the treatment of postherpetic neuralgia: a multicenter, randomized controlled study

Huang Y, Xu C, Zeng T, Li Z, Xia Y, Tao G, Zhu T, Lu L, Li J, Huang T, Huai H, Ning B, Ma C, Wang X, Chang Y, Mao P, Lin J

Background: Postherpetic neuralgia (PHN) is the most common complication of acute herpes zoster. The treatment of PHN remains a challenge for clinical pain management. Despite the effectiveness of anticonvulsants, antidepressants,...
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Comparison of ultrasonography guided serratus anterior plane block and thoracic paravertebral block in video-assisted thoracoscopic surgery: a prospective randomized double-blind study

Baytar MS, Yılmaz C, Karasu D, Baytar

Background: Various truncal block techniques with ultrasonography (USG) are becoming widespread to reduce postoperative pain and opioid requirements in video-assisted thoracoscopic surgery (VATS). The primary aim of our study was...
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Ultrasound-guided transversalis fascia plane block versus transmuscular quadratus lumborum block for post-operative analgesia in inguinal hernia repair

Fouad AZ, Abdel-Aal IRM, Ali Gadelrab MRM, Mohammed HMEHS

Background: Inguinal hernia repair is one of the most commonly performed surgical procedures. Regional blocks might provide excellent analgesia and reduce complications in the postoperative period. We aimed to compare...
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Effect of Opioids on All-cause Mortality and Opioid Addiction in Total Hip Arthroplasty: a Korea Nationwide Cohort Study

Cha Y, Jang SY, Yoo JI, Choi HG, Hwang JW, Choy W

Background: The purpose of this study was to investigate the use of opioids before and after total hip arthroplasty (THA), to find out the effect of opioid use on mortality...
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Understanding Cancer Pain and Controlling Pain: Focusing on Patients With Metastatic Urologic Cancer

Jo J, Han S, Huh JS

Urinary tumors include cancers that commonly occur throughout the population, such as bladder cancer, kidney cancer, ureter cancer, and prostate cancer. The incidence of urological tumors in Korea is increasing....
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Recovery from minimally invasive vs. open surgery in kidney cancer patients: Opioid use and workplace absenteeism

Krimphove MJ, Reese SW, Chen X, Marchese M, Pucheril D, Cone E, Chou W, Tully KH, Kibel AS, Urman RD, Chang SL, Kluth LA, Dasgupta P, Trinh QD

Purpose: Does surgical approach (minimally invasive vs. open) and type (radical vs. partial nephrectomy) affects opioid use and workplace absenteeism. Materials and Methods: Retrospective multivariable regression analysis of 2,646 opioid-naïve patients...
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Drug use evaluation of opioid analgesics in pain management among patients with hematopoietic stem cell transplantation

Oh HJ, Hong SY, Jeong YM, Choi KS, Lee E, Lee E, Kim YJ, Bang SM

Background Hematopoietic stem cell transplantation (HSCT) patients usually experience mucositis, musculoskeletal pain associated with high-dose chemotherapy, radiation, post-HSCT infection, or graft-versus-host disease. Pain management is important for the patients’ quality of...
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Effects of high-frequency, high-intensity transcutaneous electrical nerve stimulation versus intravenous opioids for pain relief after hysteroscopy: a randomized controlled study

Platon B, Thörn SE, Mannheimer C, Andréll P

Objective To compare the time spent in the Post-Anesthesia Care Unit (PACU) and the pain-relieving effects of treatment with high-frequency, high-intensity transcutaneous electrical nerve stimulation (TENS) or intravenous (IV) opioids...
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Patients’ perception about opioids and addiction in South Korea

Kim CL, Hong SJ, Lim YH, Jeong JH, Moon HS, Choi HR, Park SK, Kim JE, You H, Kim JH

Background: Chronic pain affects approximately 22% of the world’s population. Opioids can be useful in chronic pain management. However, some patients have negative perception of opioids. The purpose of this...
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Management pathway for emergency department patients in the setting of the opioid epidemic and emergency department overcrowding

Gurley K, Onyeii C, Burstein J, Grossman S

Objective The United States is currently in the midst of a major opioid addiction epidemic, of which the primary drivers are a sharp increase in prescription opioid pain medications, their...
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Protagonist Role of Opioidergic System on Post-Traumatic Stress Disorder and Associated Pain

Nikbakhtzadeh M, Borzadaran FM, Zamani E, Shabani M

Objective Post-traumatic stress disorder (PTSD) and chronic pain often co-occur. Studies have shown an interaction between pain and PTSD. In this narrative review, we aim to support conducting comprehensive studies...
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Association of trainee involvement in an acute pain service with postoperative opioid use in patients undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy

Said ET, Sztain JF, Martin EI, Abramson WB, Meineke MN, Furnish TJ, Swisher MW, Gabriel RA

Background: Several hospitals have implemented a multidisciplinary Acute Pain Service (APS) to execute surgery-specific opioid sparing analgesic pathways. Implementation of an anesthesia attending-only APS has been associated with decreased postoperative...
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Reduction of opioid intake after cooled radiofrequency denervation for sacroiliac joint pain: a retrospective evaluation up to 1 year

Tinnirello A

Background: Opioids can present intolerable adverse side-effects to patients who use these analgesics to mitigate chronic pain. In this retrospective analysis, cooled radiofrequency (CRF) denervation was evaluated to provide pain...
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All about pain pharmacology: what pain physicians should know

Kim KH, Seo HJ, Abdi S, Huh B

From the perspective of the definition of pain, pain can be divided into emotional and sensory components, which originate from potential and actual tissue damage, respectively. The pharmacologic treatment of...
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