J Korean Ophthalmol Soc.  2021 Sep;62(9):1243-1251. 10.3341/jkos.2021.62.9.1243.

Short-term Outcomes and Prognostic Factors of Cataract-combined Surgery with iStent versus iStent Inject

• Gong Y
• Hwang HB
• Kang KD
• Kim YC

• KMID: 2520206
• DOI: http://doi.org/10.3341/jkos.2021.62.9.1243

Abstract

Purpose
To analyze the therapeutic effects, prognostic factors, and complications that occurred after iStent^® or iStent inject^® implantation in South Korean glaucoma patients.
Methods
We retrospectively analyzed 42 eyes of South Korean glaucoma patients, who were followed-up for more than 6 months after iStent^® or iStent inject^® implantation alone or combined with cataract surgery. Surgical success was defined as an intraocular pressure (IOP) ≤21 mmHg and an IOP reduction ≥20% from preoperative IOP levels.
Results
The cumulative success rate at 6 months after surgery was 45.3 ± 8.1% for iStent inject^® alone (group A), 28.6 ± 13.1% for iStent^® alone (group B), 81.2 ± 6.8% for iStent inject^® combined with cataract surgery (group A-1), and 27.3 ± 21.8% for iStent^® combined with cataract surgery (group B-1). Group A-1 showed a higher success rate than group B-1 (p = 0.007); the difference in success rates between groups A and B was not statistically significant (p = 0.579). When the success prognostic factors were analyzed by Cox regression analysis, the results showed that a higher preoperative IOP was associated with a higher surgical success rate (hazard ratio 0.80, p = 0.02).
Conclusions
In our patient group, iStent inject^® was more effective than iStent^® in combination with cataract surgery. The higher the preoperative IOP, the higher the surgical success rate; the results were significant.

Keyword

Glaucoma, Intraocular pressure, iStent inject, Micro-invasive glaucoma surgery