J Korean Ophthalmol Soc.  2020 Apr;61(4):385-393. 10.3341/jkos.2020.61.4.385.

Short-term Outcomes and Prognostic Factors of iStent in the Republic of Korea

• Park SH
• Park KH
• Lee JW
• Shin J

• KMID: 2500103
• DOI: http://doi.org/10.3341/jkos.2020.61.4.385

Abstract

Purpose
To evaluate the intraocular pressure (IOP) reduction, success rate and prognostic factors after trabecular micro-bypass stent implantation in patients with open-angle glaucoma.
Methods
We retrospectively reviewed 33 eyes of 33 patients with open-angle glaucoma who were followed-up for more than 6 months after trabecular micro-bypass stent implantation. The success of surgery was defined as an IOP ≤ 21 mmHg and an IOP reduction ≥ 20% from baseline, regardless of whether glaucoma medication was used.
Results
During the follow-up at 6 months after trabecular micro-bypass stent implantation, the IOP was significantly decreased from 23.70 ± 6.26 mmHg before surgery to 18.03 ± 4.64 mmHg after 6 months, and the glaucoma medication was significantly decreased from 3.73 ± 0.67 before surgery to 3.43 ± 0.67 after 6 months (p < 0.001 and p = 0.027, respectively). The success rate at 6 months was 33.7 ± 5.5% in patients with only trabecular micro-bypass stent implantation. Using multiple regression analyses of the risk factors, age was associated with success rate (odds ratio, 1.076; 95% confidence interval, 0.996-1.164; p = 0.045).
Conclusions
In patients in the Republic of Korea, trabecular micro-bypass stent implantation was an effective surgery for IOP reduction, and showed a better surgical success rate in younger patients.

Keyword

Glaucoma; Intraocular pressure; iStent; Micro-invasive glaucoma surgery