Endocrinol Metab.  2021 Jun;36(3):572-573. 10.3803/EnM.2021.303.

Identification of Protein Z as a Potential Novel Biomarker for the Diagnosis of Prediabetes

• Koo SH

• KMID: 2517646
• DOI: http://doi.org/10.3803/EnM.2021.303

Reference

1. Ogurtsova K, da Rocha Fernandes JD, Huang Y, Linnenkamp U, Guariguata L, Cho NH, et al. IDF Diabetes Atlas: global estimates for the prevalence of diabetes for 2015 and 2040. Diabetes Res Clin Pract. 2017; 128:40–50.

2. DeFronzo RA, Ferrannini E, Groop L, Henry RR, Herman WH, Holst JJ, et al. Type 2 diabetes mellitus. Nat Rev Dis Primers. 2015; 1:15019.

3. Milman S, Crandall JP. Mechanisms of vascular complications in prediabetes. Med Clin North Am. 2011; 95:309–25.

4. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2014; 37 Suppl 1:S81–90.

5. Bonora E, Tuomilehto J. The pros and cons of diagnosing diabetes with A1C. Diabetes Care. 2011; 34 Suppl 2:S184–90.

6. Olson DE, Rhee MK, Herrick K, Ziemer DC, Twombly JG, Phillips LS. Screening for diabetes and pre-diabetes with proposed A1C-based diagnostic criteria. Diabetes Care. 2010; 33:2184–9.

7. Radin MS. Pitfalls in hemoglobin A1c measurement: when results may be misleading. J Gen Intern Med. 2014; 29:388–94.

8. Dorcely B, Katz K, Jagannathan R, Chiang SS, Oluwadare B, Goldberg IJ, et al. Novel biomarkers for prediabetes, diabetes, and associated complications. Diabetes Metab Syndr Obes. 2017; 10:345–61.

9. Bae YU, You JH, Cho NH, Kim LE, Shim HM, Park JH, et al. Association of protein Z with prediabetes and type 2 diabetes. Endocrinol Metab. 2021; 36:637–46.

10. Broze GJ Jr, Miletich JP. Human protein Z. J Clin Invest. 1984; 73:933–8.

11. Broze GJ Jr. Protein Z-dependent regulation of coagulation. Thromb Haemost. 2001; 86:8–13.

12. Fedi S, Sofi F, Brogi D, Tellini I, Cesari F, Sestini I, et al. Low protein Z plasma levels are independently associated with acute coronary syndromes. Thromb Haemost. 2003; 90:1173–8.

13. Heeb MJ, Paganini-Hill A, Griffin JH, Fisher M. Low protein Z levels and risk of ischemic stroke: differences by diabetic status and gender. Blood Cells Mol Dis. 2002; 29:139–44.