J Korean Ophthalmol Soc.  2021 May;62(5):692-696. 10.3341/jkos.2021.62.5.692.

Bilateral Calcific Band Keratopathy Treated with Dipotassium Edetic Acid

  • 1Department of Ophthalmology, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea


To report a case of bilateral calcific band keratopathy treated with dipotassium edetic acid (EDTA) in a blood collection tube, an approach that has not been used previously in the Republic of Korea.
Case summary
A 77-year-old male patient, with a history of diabetes and hypertension, presented with decreased vision in both eyes that had begun 1 year prior. Five years prior, the patient had undergone cataract surgery in the right eye and had received a diagnosis of prostate cancer for which he was currently under observation without surgical treatment. At the initial eye examination, his best-corrected visual acuity was 0.15 in the right eye and 0.1 in the left eye. Calcium deposition was observed in the center of the cornea by slit-lamp examination, resulting in a diagnosis of band keratopathy. We proceeded to dissolve the dipotassium EDTA coated on a blood collection tube with distilled water. Using the dissolved dipotassium EDTA, we peeled off the corneal epithelium under local anesthesia to remove the calcium deposition. One week after surgery, the visual acuity of both eyes improved to 0.6, and no recurrence or complications occurred for 7 months.
As a new treatment for band keratopathy, we discovered that dipotassium EDTA is more convenient to obtain than the conventional disodium EDTA. We expect that dipotassium EDTA will be widely used in the treatment of band keratopathy.


Band-shaped corneal dystrophy, Calcium chelating agents, Edetic acid
Full Text Links
  • JKOS
export Copy
  • Twitter
  • Facebook
Similar articles
Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr