J Korean Ophthalmol Soc.  2007 Nov;48(11):1459-1465.

Cosmetic Repair of Band Keratopathy Using Stained Amniotic Membrane

Affiliations
  • 1Department of Ophthalmology, Seoul National University College of Medicine, Korea.
  • 2Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Korea. eyeminerva@yahoo.co.kr
  • 3Department of Ophthalmology, Seoul National University Boramae Hospital, Seoul, Korea.
  • 4Department of Ophthalmology, Seoul National University Bundang Hospital, Gyeonggi, Korea.
  • 5Seoul National University Hospital Healthcare System Gangnam Center, Healthcare Institute, Seoul, Korea.

Abstract

PURPOSE: To evaluate the efficacy of stained amniotic membrane transplantation (AMT) for cosmetic repair of band keratopathy.
METHODS
Eight eyes from 8 patients with band keratopathy without the possibility of visual improvement were treated with corneal tattooing and stained AMT. Calcific plaques were removed with EDTA and a blade prior to the tattooing. Tattooing by the injection of tissue marking dye into the corneal stroma was performed in corneal opacities. The remaining opacity, which could not be treated with corneal tattooing, was treated with black dye-stained AMT.
RESULTS
The most common cause of band keratopathy was trauma (50%) and the mean time to epithelial healing was 11.3 days. All patients showed satisfactory results with cosmetic staining. Recurring cases and significant complications were not observed during the mean follow-up period of 7.4 months.
CONCLUSIONS
Cosmetic repair by corneal tattooing and stained AMT is an effective treatment for band keratopathy and is not associated with any significant complications.

Keyword

Band keratopathy; Corneal opacity; Corneal tattooing; Stained amniotic membrane

MeSH Terms

Amnion*
Corneal Opacity
Corneal Stroma
Edetic Acid
Follow-Up Studies
Humans
Tattooing
Edetic Acid

Figure

  • Figure 1. A 20-year-old female patient with band keratopathy in the left eye. (A) and (C): Before tattooing and stained amniotic membrane transplantation (AMT). (B) and (D): After tattooing and stained AMT.

  • Figure 2. A 63-year-old female patient with band keratopathy in the right eye. (A) and (C): Before tattooing and stained AMT. (B) and (D): After tattooing and stained AMT.


Reference

References

1. Brazier DJ, Hitchings RA. Atypical band keratopathy following long-term pilocarpine treatment. Br J Ophthalmol. 1989; 73:294–6.
Article
2. Najjar DM, Cohen EJ, Rapuano CJ, Laibson PR. EDTA chelation for calcific band keratopathy: results and long-term follow-up. Am J Ophthalmol. 2004; 137:1056–64.
Article
3. Bokosky JE, Meyer RF, Sugar A. Surgical treatment of calcific band keratopathy. Ophthalmic Surg. 1985; 16:645–7.
Article
4. Baltatzis S, Papaefthimiou J. Treatment of calcific band keratopathy by Nd:YAG laser. Eur J Ophthalmol. 1992; 2:27–9.
5. O’ Brart DPS, Gartry DS, Lohmann CP, et al. Treatment of band keratopathy by excimer laser phototherapeutic keratectomy: surgical techniques and long term follow up. Br J Ophthalmol. 1993; 77:702–8.
6. Dighiero P, Boudraa R, Ellies P, et al. Therapeutic photokeratectomy for the treatment of band keratopathy. Jr F Ophthalmol. 2000; 23:345–9.
7. Stewart OG, Morrell AJ. Management of band keratopathy with excimer phototherapeutic keratectomy: visual, refractive, and symptomatic outcome. Eye. 2003; 17:233–7.
Article
8. Anderson DF, Prabhasawat P, Alfonso E, Tseng SCG. Amniotic membrane transplantation after the primary surgical management of band keratopathy. Cornea. 2001; 20:354–61.
Article
9. Kwon YS, Song YS, Kim JC. New treatment for band keratopathy: superficial lamellar keratectomy, EDTA chelation and amniotic membrane transplantation. J Korean Med Sci. 2004; 19:611–5.
Article
10. Kim C, Han YK, Wee WR, et al. Cosmetic repair of corneal opacity by tattooing. J Korean Ophthalmol Soc. 2005; 46:1967–73.
11. Arjamaa O. EDTA chelation for calcific band keratopathy. Am J Ophthalmol. 2005; 139:216.
Article
12. Cursino JW, Fine BS. A histologic study of calcific and noncalcific band keratopathies. Am J Ophthalmol. 1976; 82:395–404.
Article
13. Meller D, Pires RT, Tseng SC. Ex vivo preservation and expansion of human limbal epithelial stem cells on amniotic membrane cultures. Br J Ophthalmol. 2002; 86:463–71.
Article
14. Tseng SC, Prabhasawat P, Lee SH. Amniotic membrane transplantation for conjunctival surface reconstruction. Am J Ophthalmol. 1997; 124:765–74.
Article
15. Tseng SC, Prabhasawat P, Barton K, et al. Amniotic membrane transplantation with or without limbal allografts for corneal surface reconstruction in patients with limbal stem cell deficiency. Arch Ophthalmol. 1998; 116:431–41.
Article
16. Kim JC, Tseng SC. Transplantation of preserved human amniotic membrane for surface reconstruction in severely damaged rabbit corneas. Cornea. 1995; 14:473–84.
Article
17. Gomes JA, Romano A, Santos MS, Dua HS. Amniotic membrane use in ophthalmology. Curr Opin Ophthalmol. 2005; 16:233–40.
Article
18. Kenyon KR. Amniotic membrane: mother's own remedy for ocular surface disease. Cornea. 2005; 24:639–42.
19. Lee JE, Jun JB, Choi HY, et al. Corneal tattooing to mask subsequent opacification after amniotic membrane grafting for stromal corneal ulcer. Acta Ophthalmol Scand. 2006; 84:696–8.
Article
20. Tang CK, Ahn HB, Park WC. The clinical effects of dye-amniotic membrane transplantation on bullous keratopathy. J Korean Ophthalmol Soc. 2003; 44:1741–7.
Full Text Links
  • JKOS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr