J Korean Assoc Oral Maxillofac Surg.  2021 Feb;47(1):40-46. 10.5125/jkaoms.2021.47.1.40.

Conservative management with Carnoy’s solution in ameloblastoma involving two unerupted teeth: a report of two cases

Affiliations
  • 1Department of Oral and Maxillofacial Surgery, School of Dentistry, Jeonbuk National University, Jeonju, Korea
  • 2Department of Oral and Maxillofaical Surgery, Section of Dentistry, Armed Forces Capital Hospital, Seongnam, Korea
  • 3Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Korea
  • 4Institute of Oral Bioscience, School of Dentistry, Jeonbuk National University, Jeonju, Korea

Abstract

Marsupialization is widely used as a primary treatment modality for reducing size of large cysts. However, there is no recommendation for specific duration of marsupialization. In addition, Carnoy’s solution usually is applied at the time of enucleation as a fixative agent. In this report, we present an appropriate marsupialization duration of ameloblastoma involving two unerupted teeth. In this present study, marsupialization using a Foley catheter was performed in two cases of ameloblastoma of the mandible involving two adjacent impacted teeth. Carnoy’s solution was applied for 3-5 minutes after enucleation in both patients. Periodically during marsupialization, the size of the radiolucency was measured in panoramic view, and clinical examination was performed. No remarkable paresthesia or soft tissue injury was observed after application of Carnoy’s solution or during follow-up. We recommend 12 to 16 weeks as an adequate marsupialization duration for a large ameloblastoma involving two impacted teeth based on increased radiopacity along the margins of the lesions. Poor oral hygiene was an issue after 12 weeks of marsupialization in one case. There were no remarkable complications with Carnoy’s solution in either case. The Foley tube has a two-way system that is more effective for irrigating the cavity than is the conventional one-way system.

Keyword

Ameloblastoma; Decompression; Carnoy’s solution; Conservative treatment

Figure

  • Fig. 1 A. Panoramic view on the first visit (4.2 cm×2.0 cm). B, C. Computed tomography coronal view on the first visit. D. Periapical standard radiograph on the first visit. E. Intraoral photo just after marsupialization using the Foley tube.

  • Fig. 2 A. 16-Fr Foley catheter (Yushin Medical & Trading). B. Cross-section of the Foley catheter.

  • Fig. 3 Panoramic view at (A) first visit, (B) 10 weeks after marsupialization, and (C) 15 weeks after marsupialization.

  • Fig. 4 A. Preoperative intraoral lesion. B. Removal of the main mass (4.5 cm×2 cm) and small mass (2 cm×1.5 cm). C. #46 distal root resorption. D. Postoperative panoramic view.

  • Fig. 5 A. Open dressing with furacin gauze was changed twice a week. B. Seven weeks after enucleation.

  • Fig. 6 Radiograph on the first visit. A. Panoramic view (4.5 cm×8.1 cm). B. Coronal view on computed tomography (CT), mandibular cortical bone was flattened and dilated. C. On sagittal CT, the mandibular inferior border was very thin.

  • Fig. 7 A. First visit. B. At seven weeks of marsupialization, increase of radiopacity on the superior border of the lesion and woven bone formation on the margin of the lesion were noted. C. At 16 weeks of marsupialization, radiopacity was increased, although the size of the lesion did not exhibit remarkable change.

  • Fig. 8 A. Postoperative panoramic view. B. Removal of the main mass (4 cm×5.5 cm) and a small mass (2 cm×2.5 cm).

  • Fig. 9 Radiograph after 22 weeks of marsupialization. A. Panoramic view on #45 distal, posterior, and inferior borders of the lesion: radiopacity was increased. B. Coronal view on computed tomography (CT): new bone formation was observed along the mass removal area. C. Sagittal view on CT: new bone formation was observed along the mass removal area. D. Intraoral photograph at 22 weeks of cyst enucleation: furacin gauze was changed every week. E. Soft tissue healing was observed after 22 weeks of cyst enucleation.


Reference

References

1. Hou R, Zhou H. 2013; Articles of marsupialization and decompression on cystic lesions of the jaws: a literature review. J Oral Maxillofac Surg Med Pathol. 25:299–304. https://doi.org/10.1016/j.ajoms.2013.06.007 .
Article
2. Haq J, Siddiqui S, McGurk M. 2016; Argument for the conservative management of mandibular ameloblastomas. Br J Oral Maxillofac Surg. 54:1001–5. https://doi.org/10.1016/j.bjoms.2016.07.017 . DOI: 10.1016/j.bjoms.2016.07.017. PMID: 27599408.
Article
3. Barnes L, Eveson JW, Reichart P, Sidransky D. 2005. WHO classification of tumours: pathology and genetics of head and neck tumours. 3rd ed. IARC Publications;Lyon:
4. Gao L, Wang XL, Li SM, Liu CY, Chen C, Li JW, et al. 2014; Decompression as a treatment for odontogenic cystic lesions of the jaw. J Oral Maxillofac Surg. 72:327–33. https://doi.org/10.1016/j.joms.2013.07.035 . DOI: 10.1016/j.joms.2014.03.035. PMID: 24947962.
Article
5. Cahn LR. 1933; The dentigerous cyst is a potential adamantinoma. Dent Cosm. 75:889–93.
6. Cutler EC, Zollinger R. 1933; The use of sclerosing solutions in the treatment of cysts and fistulae. Am J Surg. 19:411–8. https://doi.org/10.1016/S0002-9610(33)90796-5 .
Article
7. Huang IY, Lai ST, Chen CH, Chen CM, Wu CW, Shen YH. 2007; Surgical management of ameloblastoma in children. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 104:478–85. https://doi.org/10.1016/j.tripleo.2007.01.033 . DOI: 10.1016/j.tripleo.2007.01.033. PMID: 17524681.
Article
8. Maia EC, Sandrini FAL. 2017; Management techniques of ameloblastoma: a literature review. Rev Gaúcha Odontol. 65:62–9. https://doi.org/10.1590/1981-863720170001000093070 .
Article
9. Korzhevskiĭ DE. 2001; [Silver nitrate impregnation of internuclear structures in nerve cells following fixation in Carnoy’s medium]. Morfologiia. 119:67–9. Russian.
10. Lee PK, Samman N, Ng IO. 2004; Unicystic ameloblastoma--use of Carnoy’s solution after enucleation. Int J Oral Maxillofac Surg. 33:263–7. https://doi.org/10.1006/ijom.2003.0496 .
Article
11. Kalaskar R, Unawane AS, Kalaskar AR, Pandilwar P. 2011; Conservative management of unicystic ameloblastoma in a young child: report of two cases. Contemp Clin Dent. 2:359–63. https://doi.org/10.4103/0976-237X.91804 . DOI: 10.4103/0976-237X.91804. PMID: 22346168. PMCID: PMC3276868.
Article
12. Nakamura N, Higuchi Y, Mitsuyasu T, Sandra F, Ohishi M. 2002; Comparison of long-term results between different approaches to ameloblastoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 93:13–20. https://doi.org/10.1067/moe.2002.119517 . DOI: 10.1067/moe.2002.119517. PMID: 11805772.
Article
13. Motamedi MH, Talesh KT. 2005; Management of extensive dentigerous cysts. Br Dent J. 198:203–6. https://doi.org/10.1038/sj.bdj.4812082 . DOI: 10.1038/sj.bdj.4812082. PMID: 15731795.
Article
14. Martínez-Pérez D, Varela-Morales M. 2001; Conservative treatment of dentigerous cysts in children: a report of 4 cases. J Oral Maxillofac Surg. 59:331–3. https://doi.org/10.1053/joms.2001.21006 . DOI: 10.1053/joms.2001.21006. PMID: 11243619.
Article
15. Assael LA. Peterson LJ, Indresano TA, Marciani RD, Roser SM, editors. 1992. Surgical management of odontogenic cysts and tumors. Principles of oral and maxillofacial surgery. Lippincott;Philadelphia: p. 685–8.
16. Frerich B, Cornelius CP, Wiethölter H. 1994; Critical time of exposure of the rabbit inferior alveolar nerve to Carnoy’s solution. J Oral Maxillofac Surg. 52:599–606. https://doi.org/10.1016/0278-2391(94)90098-1 .
Article
17. Sivanmalai S, Kandhasamy K, Prabu N, Prince CN, Prabu CS. 2012; Carnoy’s solution in the mangement of odontogenic keratocyst. J Pharm Bioallied Sci. 4(Suppl 2):S183–5. https://doi.org/10.4103/0975-7406.100266 .
Article
18. Lau SL, Samman N. 2006; Recurrence related to treatment modalities of unicystic ameloblastoma: a systematic review. Int J Oral Maxillofac Surg. 35:681–90. https://doi.org/10.1016/j.ijom.2006.02.016 . DOI: 10.1016/j.ijom.2006.02.016. PMID: 16782308.
Article
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