Asian Spine J.  2021 Feb;15(1):117-126. 10.31616/asj.2019.0161.

Use of Platelet-Rich Plasma in Treating Low Back Pain: A Review of the Current Literature

Affiliations
  • 1Department of Surgical Oncology, Dyson Cancer Center, Health Quest Health Systems/Nuvance Health, Poughkeepsie, NY, USA
  • 2Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA
  • 3Medical College, Aga Khan University Hospital, Karachi, Pakistan
  • 4Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan
  • 5Department of Neurology, Aga Khan University Hospital, Karachi, Pakistan
  • 6Department of Neurosurgery, Aga Khan University Hospital, Karachi, Pakistan

Abstract

Low back pain (LBP) is a common problem encountered by physicians. It is a considerable cause of morbidity and socioeconomic loss and is one of the most expensive musculoskeletal disorders. Conventional treatments include bed rest, analgesics, therapeutic exercises, lumbar or caudal epidural corticosteroids, and surgery. Several new biological therapies are being investigated for use in LBP and one of these is platelet-rich plasma (PRP). In this article, we summarize the current literature published on PRP concerning its composition, classification, and application in LBP. We believe our review will prove useful to clinicians and academics alike, interested in new developing therapies for LBP.

Keyword

Platelet-rich plasma; Low back pain; Radiculopathy; Epidural
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