J Periodontal Implant Sci.  2020 Dec;50(6):406-417. 10.5051/jpis.2000400020.

Open healing of contained and noncontained extraction sockets covered with a ribose cross-linked collagen membrane: a pilot study

• Friedmann A
• Meskeleviciene V
• Yildiz MS
• Götz W
• Park JC
• Fischer KR

• KMID: 2511812
• DOI: http://doi.org/10.5051/jpis.2000400020

Abstract

Purpose
This study investigated whether the placement of ribose cross-linked collagen (RCLC) membranes without primary soft tissue closure predictably resulted in sufficient alveolar ridge preservation in contained and non-contained extraction sockets.
Methods
Membranes were positioned across extraction sockets, undermining full-thickness flaps, and the gingival margins were fixed by double-interrupted sutures without crossed horizontal mattress sutures for 1 week. In non-contained sockets, a bone substitute was used to support the membrane within the bony envelope. Radiographs and clinical images obtained 4 months later were analyzed by ImageJ software using non-parametric tests.
Results
In 18 patients, 20 extraction sockets healed uneventfully and all sites received standard-diameter implants (4.1, 4.8, or 5.0 mm) without additional bone augmentation. Soft tissues and the muco-gingival border were well maintained. A retrospective analysis of X-rays and clinical photographs showed non-significant shrinkage in the vertical and horizontal dimensions (P=0.575 and P=0.444, respectively). The new bone contained vital bone cells embedded in mineralized tissues.
Conclusions
Within the limitations of this pilot study, open healing of RCLC membranes may result in sufficient bone volume for implant placement without additional bone augmentation in contained and non-contained extraction sockets.

Keyword

Bone regeneration; Epithelial tissue; Guided tissue regeneration; Tooth extraction; Wound healing