Korean J Med.  2020 Oct;95(5):344-348. 10.3904/kjm.2020.95.5.344.

A Case of Sweet’s Syndrome with Acute Kidney Injury in a Patient with Myelodysplastic Syndrome

Affiliations
  • 1Division of Nephrology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
  • 2Division of Hematology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
  • 3Division of Nephrology, Department of Internal Medicine, Cheonan Medical Center, Cheonan, Korea
  • 4Division of Nephrology, Department of Internal Medicine, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Korea

Abstract

Sweet’s syndrome (SS) is an autoimmune-mediated acute febrile neutrophilic dermatosis with a number of possible etiologies, including infection, malignancy, and drug reactions. In contrast to its original description, it can rarely involve extracutaneous organs, including the central nervous system, cardiovascular system, lung, liver, gastrointestinal tract, spleen, and bone. To our knowledge, there have been only three cases of SS accompanied by acute kidney injury worldwide, and this is the first report in which the patient recovered completely from acute kidney injury as well as cutaneous lesions with early steroid administration. Here, we report a case of SS with acute kidney injury in a patient with myelodysplastic syndrome (MDS) whose skin lesions and renal function recovered fully with early diagnosis and steroid therapy along with a review of the relevant literature.

Keyword

Sweet 증후군; 골수 이형성 증후군; 급성신손상; Sweet syndrome; Myelodysplastic syndromes; Acute kidney injury
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