Clin Endosc.  2020 Sep;53(5):611-614. 10.5946/ce.2019.151.

Acute Pancreatitis: A Rare Post-Colonoscopy Sequela

Affiliations
  • 1Department of Gastroenterology, Topiwala National Medical College and B.Y.L Nair Charitable Hospital, Mumbai, India

Abstract

Abdominal pain is a common but benign symptom after colonoscopy. We report a case of acute pancreatitis that occurred just after an elective screening colonoscopy; this is a rare event with very few reported cases. A healthy, asymptomatic male underwent screening colonoscopy at our center and developed abdominal pain and emesis after the procedure. An abdominal X-ray ruled out perforation but laboratory tests revealed elevated levels of amylase and lipase. The patient had no etiological risk factors for pancreatitis. The presumed mechanism of pancreatitis in this case is mechanical and pressure trauma from excessive insufflation, external abdominal pressure, and repeated withdrawal of the colonoscope due to tight angulation of the splenic flexure, a structure that is in close proximity to the pancreatic tail. Acute pancreatitis should be considered in the differential diagnosis of patients who present with abdominal pain after colonoscopy once more common etiologies have been excluded.

Keyword

Pancreatitis; Post colonoscopy; Splenic flexure

Figure

  • Fig. 1. A erect abdominal X-ray demonstrating a distended splenic flexure (blue arrow) and absence of free air under diaphragm.

  • Fig. 2. Contrast-enhanced computed tomography of the abdomen demonstrating a bulky body and tail of the pancreas with mild peripancreatic fat stranding, findings that are consistent with acute pancreatitis (blue arrow).


Reference

1. Cotton PB, Eisen GM, Aabakken L, et al. A lexicon for endoscopic adverse events: report of an ASGE workshop. Gastrointest Endosc. 2010; 71:446–454.
Article
2. Ko CW, Dominitz JA. Complications of colonoscopy: magnitude and management. Gastrointest Endosc Clin N Am. 2010; 20:659–671.
Article
3. ASGE Standards of Practice Committee, Fisher DA, Maple JT, et al. Complications of colonoscopy. Gastrointest Endosc. 2011; 74:745–752.
Article
4. Bilbao MK, Dotter CT, Lee TG, Katon RM. Complications of endoscopic retrograde cholangiopancreatography (ERCP). A study of 10,000 cases. Gastroenterology. 1976; 70:314–320.
5. Nevins AB, Keeffe EB. Acute pancreatitis after gastrointestinal endoscopy. J Clin Gastroenterol. 2002; 34:94–95.
Article
6. Ko HH, Jamieson T, Bressler B. Acute pancreatitis and ileus post colonoscopy. Can J Gastroenterol. 2009; 23:551–553.
7. Thomas AW, Mitre RJ. Acute pancreatitis as a complication of colonoscopy. J Clin Gastroenterol. 1994; 19:177–178.
Article
8. Sidiqi MM, Gong B. Acute pancreatitis as a complication of routine colonoscopy-a rare case report. Int J Surg Case Rep. 2019; 57:81–83.
Article
9. Shekhar S, Singh S, Gupta S. Postcolonoscopy pancreatitis. Endoscopy. 2014; 46(Suppl 1):E515–E516.
Article
10. Khashram M, Frizelle FA. Colonoscopy--a rare cause of pancreatitis. N Z Med J. 2011; 124:74–76.
11. Limb C, Ibrahim IA, Fitzsimmons S, Harper AJ. Recurrent pancreatitis after unremarkable colonoscopy, temporalised by CT imaging: an unusual case. BMJ Case Rep. 2016; 2016:bcr2015213192.
Article
12. Honda K, Mizutani T, Nakamura K, et al. Acute pancreatitis associated with peroral double-balloon enteroscopy: a case report. World J Gastroenterol. 2006; 12:1802–1804.
Article
13. Groenen MJ, Moreels TG, Orlent H, Haringsma J, Kuipers EJ. Acute pancreatitis after double-balloon enteroscopy: an old pathogenetic theory revisited as a result of using a new endoscopic tool. Endoscopy. 2006; 38:82–85.
Article
14. Blackwood WD, Vennes JA, Silvis SE. Post-endoscopy pancreatitis and hyperamylasuria. Gastrointest Endosc. 1973; 20:56–58.
Article
15. Kobayashi T, Fukuchi S, Sawano S, Yamada N, Ikenaga T, Sugimoto T. Changes in serum isoamylase activities after fibergastroduodenoscopy and colonoscopy. Isoamylase after FGDS and FCS. Endoscopy. 1979; 11:133–137.
Article
16. McCutcheon AD. A fresh approach to the pathogenesis of pancreatitis. Gut. 1968; 9:296–310.
Article
17. Raper SE. Acute pancreatitis secondary to dehydration: case report and review of the literature. Am Surg. 1999; 65:1084–1087.
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