Korean J Otorhinolaryngol-Head Neck Surg.  2020 Jul;63(7):319-323. 10.3342/kjorl-hns.2019.00227.

Mucosa-Associated Lymphoid Tissue Lymphoma Arising from the Ethmoid Sinus Mucosa: A Case Report and Review of the Literature

Affiliations
  • 1Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Korea
  • 2Department of Pathology, Yonsei University College of Medicine, Seoul, Korea
  • 3The Airway Mucus Institute, Yonsei University College of Medicine, Seoul, Korea

Abstract

Most of nasal cavity or paranasal sinuses lymphoma reported in Korea is either diffuse large Bcell lymphoma or natural killer/T-cell lymphoma. There are only three cases of mucosa-associated lymphoid tissue lymphoma (MALTOMA), which has so far been reported only in a Korea journal and all of which have occurred in the nasal cavity and in the turbinate. We experienced a case of MALTOMA of ethmoid sinus extending to the orbital cavity. It was confirmed by the findings of immunohistochemical staining (positive with CD20, Bcl-2, and Granzyme B, negative with CD5, CD56, Bcl-6 and Cyclin D1). The patient underwent radiation therapy and the lesion was successfully resolved without recurrence for 16 months.

Keyword

B-cell; Lymphoma; Mucosa-associated lymphoid tissue; Paranasal
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