Korean J Otorhinolaryngol-Head Neck Surg.
2020 Jul;63(7):319-323. 10.3342/kjorl-hns.2019.00227.
Mucosa-Associated Lymphoid Tissue Lymphoma Arising from the Ethmoid Sinus Mucosa: A Case Report and Review of the Literature
- Affiliations
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- 1Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Korea
- 2Department of Pathology, Yonsei University College of Medicine, Seoul, Korea
- 3The Airway Mucus Institute, Yonsei University College of Medicine, Seoul, Korea
- KMID: 2504991
- DOI: http://doi.org/10.3342/kjorl-hns.2019.00227
Abstract
- Most of nasal cavity or paranasal sinuses lymphoma reported in Korea is either diffuse large Bcell lymphoma or natural killer/T-cell lymphoma. There are only three cases of mucosa-associated lymphoid tissue lymphoma (MALTOMA), which has so far been reported only in a Korea journal and all of which have occurred in the nasal cavity and in the turbinate. We experienced a case of MALTOMA of ethmoid sinus extending to the orbital cavity. It was confirmed by the findings of immunohistochemical staining (positive with CD20, Bcl-2, and Granzyme B, negative with CD5, CD56, Bcl-6 and Cyclin D1). The patient underwent radiation therapy and the lesion was successfully resolved without recurrence for 16 months.
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