Korean J Otolaryngol-Head Neck Surg.  2006 Dec;49(12):1227-1230.

Mucosa-Associated Lymphoid Tissue Lymphoma Arising from the Nasal Mucosa: A Case Report and Review of the Literature

Affiliations
  • 1Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School, Gwangju, Korea. limsc@chonnam.ac.kr
  • 2Chonnnam National University Hwasun Hospital, Hwasun, Korea.

Abstract

Most extranodal lymphomas arise in the gastrointestinal tract, but the other mucosal organs are rarely involved. We report a case of primary mucosa-associated lymphoid tissue (MALT) lymphoma of the nasal cavity. A 65-year-old woman was refered to our hospital with a history of prolonged epiphora in the left eye. Although nasal examination suggested normal except marked mucosal thickening of the inferior turbinate, partial inferior turbinectomy and biopsy revealed subepithelial infiltration of atypical lymphoid cells that stained for CD20, CD79a, and BCL-2 ; stained weakly for CD43, and this patient was finally diagnosed as having primary MALT lymphoma of the nasal cavity. This patient achieved complete remission after radiation therapy, and she remains free of disease for 6 months.

Keyword

Mucosa-assoicated lymphoid tissue lymphoma; Nasal mucosa

MeSH Terms

Aged
Biopsy
Female
Gastrointestinal Tract
Humans
Lacrimal Apparatus Diseases
Lymphocytes
Lymphoid Tissue
Lymphoma
Lymphoma, B-Cell, Marginal Zone*
Nasal Cavity
Nasal Mucosa*
Turbinates
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