Yonsei Med J.  2005 Aug;46(4):562-566. 10.3349/ymj.2005.46.4.562.

Mucosa-Associated Lymphoid Tissue Lymphoma of the Esophagus Coexistent with Bronchus-Associated Lymphoid Tissue Lymphoma of the Lung

• Chung JJ
• Kim MJ
• Kie JH
• Kim KW

• KMID: 1716528
• DOI: http://doi.org/10.3349/ymj.2005.46.4.562

Abstract

Non-Hodgkin's lymphoma very rarely involves the esophagus, occurring in less than 1% of patients with gastrointestinal lymphoma. A few cases of mucosa-associated lymphoid tissue (MALT) lymphoma of the esophagus have been reported in the English literature. To our knowledge, there has been no report of MALT lymphoma of the esophagus coexistent with bronchus-associated lymphoid tissue lymphoma (BALT) of the lung. This report details the radiological and clinical findings of this first concurrent case.

Keyword

Esophagus; MALT lymphoma; lung; BALT lymphoma

MeSH Terms

Aged
Bronchi/pathology
Esophageal Neoplasms/*pathology/radiography
Humans
Lung Neoplasms/*pathology/radiography
Lymphoma/*pathology/radiography
Lymphoma, Mucosa-Associated Lymphoid Tissue/*pathology/radiography
Male
Neoplasms, Multiple Primary/*pathology/radiography

Figure

• 

  Fig. 1 A 65-year-old man with esophageal MALT lymphoma and concurrent BALT lymphoma of the lung. (A) A barium swallow study revealed a well-demarcated submucosal mass (arrowheads) of 10×3×3 cm in size in the upper thoracic esophagus without surface ulceration or a stalk. (B) A chest CT scan showed a sharply demarcated homogeneous mass within the esophagus. Note the eccentric location, crescent-shape esophageal lumen (compressed by the mass), and the laterally displaced trachea. (C) A chest CT scan of the lower lung showed an ill-defined 4×3 cm size mass in the lateral basal segment of the lower lobe of the left lung. A small focal subpleural consolidation was also seen in the right lower lung; however, this consolidation was not seen in the follow-up CT scan taken before chemotherapy. (D) Upon histologic examination, dense atypical lymphocytic infiltrations were noted in the submucosa of esophagus. The tumor cells showed dark nuclei with abundant clear cytoplasm and occasional Dutcher bodies (H & E stain, ×200). (E) Upon immunohistochemical stain, the esophageal tumor cells showed extensive strong immunoreactivity for the B-cell marker and L26, and monoclonal reactivity for kappa light chain immunoglobulin along the cytoplasmic membranes (×200).

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