J Korean Diabetes.  2020 Jun;21(2):64-68. 10.4093/jkd.2020.21.2.64.

Glucose Metabolism in Pregnant Women with Normal Glucose Tolerance

• Koo BK

• KMID: 2503961
• DOI: http://doi.org/10.4093/jkd.2020.21.2.64

Abstract

Insulin resistance increases from conception into late pregnancy in women with normal glucose tolerance as well as women with gestational diabetes. Increasing insulin resistance during pregnancy permits adequate supply of glucose from the maternal side to the fetus. Understanding normal physiologic changes in glucose metabolism would help understand the pathophysiology of gestational diabetes mellitus.

Keyword

Diabetes, gestational; Hyperglycemia; Insulin resistance

Figure

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  Fig. 1. Interstitial glucose level monitored by continuous glucose monitoring system during pregnancy. (A) Diurnal glucose level of women at 28∼36 weeks’ of gestation. (B) Maternal glucose level after meal according to the presence (■) or absence (●) of obesity at 30 weeks’ of gestation.

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