J Korean Acad Oral Health.  2020 Jun;44(2):67-72. 10.11149/jkaoh.2020.44.2.67.

Effectiveness of mentha extracts against oral microorganisms: an in vitro study

Affiliations
  • 1Feagle Co., Ltd.,
  • 2Department of Oral Anatomy, School of Dentistry, Pusan National University, Yangsan, Korea
  • 3Department of Dental Hygiene, Kyungnam College of Information & Technology, Busan, Korea

Abstract


Objectives
Dental caries and periodontal disease are infectious and chronic diseases. The aim of the study was to investigate the antimicrobial effect of mentha extracts against Streptococcus mutans (S. mutans ) and Porphyromonas gingivalis (P. gingivalis ).
Methods
This activity of mentha extracts were confirmed by the disk diffusion test and minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and colony forming unit (CFU) assays.
Results
S. mutans and P. gingivalis showed the highest antimicrobial activity within the inhibition zones. The antimicrobial activity was interrupted as the MIC and MBC of the herbal extracts against the two bacteria were 1 mg/ml and 10 mg/ml, respectively. The antimicrobial effect was determined by the CFU assay.
Conclusions
Mentha herb extract demonstrated potential antimicrobial activity against S. mutans and P. gingivalis that cause dental caries and periodontal disease.

Keyword

Antimicrobial effect; Mentha extracts; Porphyromonas gingivalis; Streptococcus mutans

Figure

  • Fig. 1 The clear zone of oral pathogens by mentha herb extracts.

  • Fig. 2 The colony forming unit (CFU) of oral pathogens by mentha herb extracts.

  • Fig. 3 Growth inhibition of oral pathogens by mentha herb extracts (*P<0.001). (A) S. mutans, (B) P. gingivalis.


Reference

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