Korean J Ophthalmol.  2020 Jun;34(3):235-241. 10.3341/kjo.2019.0126.

Tomographic Structural Changes of the Inner Retina after Internal Limiting Membrane Peeling for Idiopathic Epiretinal Membrane

• Han GH
• Han DJ
• Lee JH
• Byeon SH
• Shin JY

• KMID: 2502652
• DOI: http://doi.org/10.3341/kjo.2019.0126

Abstract

Purpose
To investigate the tomographic structural changes in the retinal layers after internal limiting membrane (ILM) peeling for idiopathic epiretinal membrane (ERM).
Methods
Sixty-nine eyes treated with vitrectomy and ILM peeling for idiopathic ERM were analyzed. Parafoveal retinal thickness was measured at baseline and 6 months after surgery.
Results
Total retinal thickness decreased significantly in the nasal and temporal subfields after surgery (p < 0.001), whereas the inner nuclear layer and outer nuclear layer showed nasal thickening (all, p < 0.001). The postoperative temporal/nasal subfield thickness ratio of each layer was significantly lower than that of fellow eyes. Eyes with larger ILM peeling showed a significantly lower temporal/nasal subfield thickness ratio (p = 0.033) than those with smaller sizes.
Conclusions
The retinal thickness of each layer showed anatomical changes from ILM peeling and ERM removal. Nasal parafoveal thickening and temporal thinning occurred in the inner retinal architecture, which might be affected by ILM peeling size.

Keyword

Epiretinal membrane; Internal limiting membrane; Optical coherence tomography; Retinal layer segmentation; Retinal nerve fiber layer