Korean J Fam Pract.  2020 Feb;10(1):53-59. 10.21215/kjfp.2020.10.1.53.

Association of Serum Vitamin D Status with Prediabetes and Prehypertension in Korean Adults: An Analysis of the 2013–2015 Korea National Health and Nutrition Examination Survey Data

• Park J
• Nam GE
• Choo J
• Park H
• Lee SJ
• Park S
• Chung S
• Lee ES
• Huh Y
• Kim W
• Kwon Y
• Kim YH
• Cho KH

• KMID: 2501909
• DOI: http://doi.org/10.21215/kjfp.2020.10.1.53

Abstract

Background
Recent studies have indicated that vitamin D deficiency is associated with diabetes and hypertension in adults. However, this association has not been sufficiently studied in cases of prediabetes and prehypertension. Thus, this study aimed to clarify the relationship between vitamin D levels and prediabetes and prehypertension in Korean adults.
Methods
Data from 1,808 adults aged ≥19 years who participated in the 2013–2015 Korea National Health and Nutrition Examination Survey were included in this study. The odds ratio of prediabetes and prehypertension according to the 25-hydroxyvitamin D (25[OH]D) status was calculated using multivariable logistic regression analysis.
Results
Mean serum 25(OH)D levels were significantly different among females with normal glucose levels, prediabetes, and diabetes mellitus. Further, the mean levels were not significantly different in both males and females of all ages with normal blood pressure, prehypertension, and hypertension. In addition, logistic regression analysis showed that serum 25(OH)D levels were not significantly associated with the odds ratio of prediabetes and prehypertension after adjusting for age, sex, smoking, alcohol consumption, physical activity, calcium supplement intake, income, body mass index, systolic blood pressure, and fasting glucose.
Conclusion
Serum vitamin D status was not independently associated with the risks of prediabetes and prehypertension in Korean adults.

Keyword

Vitamin D; 25-Hydroxyvitamin D; Prediabetes; Prehypertension; Korea National Health and Nutrition Examination Survey