Korean J Med.
2020 Apr;95(2):89-94. 10.3904/kjm.2020.95.2.89.
Osteoporosis in Patients with Chronic Kidney Disease
- Affiliations
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- 1Division of Nephrology, Department of Internal Medicine, Korea University Guro Hospital, Seoul, Korea
- KMID: 2501901
- DOI: http://doi.org/10.3904/kjm.2020.95.2.89
Abstract
- Osteoporosis in chronic kidney disease (CKD) is also referred to as ‘CKD with low bone mineral density (BMD)’, because the cause of low BMD in CKD includes chronic kidney disease-mineral bone disorders (CKD-MBD) such as secondary hyperparathyroidism, osteomalacia, and adynamic bone disease. Diagnostic methods of osteoporosis in CKD include FRAX®, BMD, and bone turnover markers as well as CKD-MBD biochemical parameters- calcium, P, alkaline phosphatase, PTH, and 25(OH)D3. The management of osteoporosis in CKD prioritizes CKD-MBD management over selection of bone anti-resorptive agents or osteo-anabolic agents according to clinical and laboratory findings.
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