Arch Craniofac Surg.
2020 Apr;21(2):132-136. 10.7181/acfs.2019.00633.
Primary amelanotic melanoma of the mandibulargingiva
- Affiliations
-
- 1Pop Plastic Surgery Clinic, Seoul, Korea
- 2Departments of Plastic and Reconstructive Surgery, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea
- 3Departments of Otolaryngology-Head and Neck Surgery, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea
- 4Departments of Pathology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea
- KMID: 2500258
- DOI: http://doi.org/10.7181/acfs.2019.00633
Abstract
- Oral mucosal melanoma is a very rare type of malignant melanoma, the characteristics of which differ from those of cutaneous melanoma. Primary amelanotic melanoma of the mandibular gingiva, which can invade the mandibular bone, is very rare worldwide. Here, we report a case in which we performed a reconstruction of the mandible and gingiva using the fibula osteocutaneous free flap procedure to treat a patient diagnosed with a primary amelanotic melanoma of the mandibular gingiva. The procedure was successful, and no recurrence was observed 10 months after surgery. Oral mucosal melanoma has a much poorer prognosis and a lower 5-year survival rate than cutaneous melanoma. However, recently, immunomodulatory therapies for mutations in melanocytic lesions have been used effectively to treat the increasing number of patients developing this type of melanoma, thus improving the prognosis of patients with oral mucosal melanoma.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Immunohistochemistry: sole tool in diagnosing a rare case of primary vaginal amelanotic melanoma
- An Ulcerative Amelanotic Melanoma on the Heel
- Polypoid Amelanotic Melanoma on the Thigh
- Cytologic features of primary amelanotic melanoma of the vagina: a case report
- Primary malignant melanoma of the esophagus
