Res Vestib Sci.  2019 Dec;18(4):111-117. 10.21790/rvs.2019.18.4.111.

Comparison of Treatment Outcomes between Intratympanic Steroid Injection and Oral Diuretics in Patients with Acute Low Frequency Sensorineural Hearing Loss with Vertigo

Affiliations
  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea. an0072@hanmail.net

Abstract


OBJECTIVES
Sudden sensorineural hearing loss and Meniere disease can be managed with intratympanic steroid injection (ITSI) as a primary treatment. The aim of this study was to compare the effectiveness of ITSI versus oral diuretics for acute low frequency sensorineural hearing loss (LFHL) with vertigo.
METHODS
A total 76 patients with LFHL that had developed within previous 2 weeks were enrolled and categorized into 2 groups: treated with ITSI four times on 4 consecutive days (ITSI group; 42 patients) and treated with diuretics orally for 2 weeks (diuretics group; 34 patients). After 6 months, we analyzed treatment outcomes using subjective improvement and audiometric change.
RESULTS
Hearing thresholds at low frequencies ≤500 Hz were significantly improved in both ITSI and diuretics group (p<0.05). The cure rate of ITSI group was not significantly higher than that of diuretics group (54.8% vs. 52.9%, p>0.05). For subjective symptoms, there were no significant differences of improvement rate in both groups (ITSI 64.3% vs. diuretics 61.8%, p>0.05). In pure tone audiometry, the improvement rate of ITSI group was not significantly different from that of diuretics group (78.6% vs. 70.6%, p>0.05). There was a significant correlation between the cure rate and duration of symptoms.
CONCLUSIONS
Both ITSI and diuretics are effective treatment modalities for acute LFHL with vertigo within 2 weeks of development. There is no difference of treatment outcomes between ITSI and diuretics in patients with acute LFHL and vertigo.

Keyword

Sensorineural hearing loss; Vertigo; Steroids; Diuretics

MeSH Terms

Audiometry
Diuretics*
Hearing
Hearing Loss, Sensorineural*
Humans
Meniere Disease
Steroids
Vertigo*
Diuretics
Steroids
Full Text Links
  • RVS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
    DB Error: unknown error