Asia Pac Allergy.  2020 Jan;10(1):e6. 10.5415/apallergy.2020.10.e6.

A 5-year retrospective review of children with peanut allergy in the largest paediatric hospital in Singapore

• Lee MP
• Saffari SE
• Loh W
• Goh SH
• Goh A
• Chiang WC
• Chong KW

• KMID: 2469859
• DOI: http://doi.org/10.5415/apallergy.2020.10.e6

Abstract

BACKGROUND
The prevalence of peanut allergy (PA) among children has increased significantly over the past decade. Even though the prevalence of PA in Singapore is considered low, peanut is the top trigger for food-induced anaphylaxis in Singaporean children.
OBJECTIVE
To describe the demographic characteristics and clinical features of children with PA.
METHODS
This is a 5-year retrospective review of children diagnosed with PA based on clinical history coupled with a positive skin prick test to peanut or positive oral food challenge results.
RESULTS
There were 269 patients (53.9% males) with a clinical diagnosis of PA. The median age at first allergic presentation for the PA group was 24 months old, with interquartile range of 13-39 months. The most common form of peanut introduced was roasted peanut. The rate of peanut anaphylaxis was 7.1%. Concomitant tree nut sensitization was found in 32.3% of this cohort, predominantly to cashew nut. Majority of them have a personal history of atopy - 75.8% with eczema, 63.6% with allergic rhinitis, and 19.7% with asthma.
CONCLUSION
This is the first large review of peanut-allergic children in Singapore. Prospective population-based studies are needed to establish the true prevalence and risk factors associated with the development of this potentially life-threatening condition.

Keyword

Peanut allergy; Children; Singapore; Asia

MeSH Terms

Anacardium
Anaphylaxis
Arachis*
Asia
Asthma
Child*
Cohort Studies
Diagnosis
Eczema
Humans
Nuts
Peanut Hypersensitivity*
Prevalence
Prospective Studies
Retrospective Studies*
Rhinitis, Allergic
Risk Factors
Singapore*
Skin
Trees

Reference

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