Nucl Med Mol Imaging.  2019 Dec;53(6):442-445. 10.1007/s13139-019-00621-x.

68Ga-PSMA: a One-stop Shop in Radioactive Iodine Refractory Thyroid Cancer?

Affiliations
  • 1Department of Nuclear Medicine, University of Pretoria & Steve Biko Academic Hospital, Private Bag X169, Pretoria 0001, South Africa. mike.sathekge@up.ac.za

Abstract

We report a case of a 47-year-old female known with metastatic papillary thyroid cancer. Her treatment history included total thyroidectomy and 3 previous radio ablations with a cumulative dose of 950 mCi of ¹³¹I. On follow-up, her thyroglobulin levels had demonstrated a rising trend (from 3789.0 to 4240.0 ug/L) despite a ¹²³I whole-body scan demonstrating a reduction in tracer avid lesions. She was suspected of having radio-resistant disease. The patient underwent both ¹â¸F-FDG and ⁶⁸Ga-PSMA PET/CT imaging with both scans demonstrating congruent lesions however with far greater intensity on the ⁶⁸Ga-PSMA study.

Keyword

⁶⁸Ga-PSMA; ¹⁸F-FDG; Thyroid cancer; Radioactive iodine refractory thyroid

MeSH Terms

Female
Follow-Up Studies
Humans
Iodine*
Middle Aged
Positron-Emission Tomography and Computed Tomography
Thyroglobulin
Thyroid Gland*
Thyroid Neoplasms*
Thyroidectomy
Iodine
Thyroglobulin
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