Epidemiol Health.  2019;41:e2019037. 10.4178/epih.e2019037.

Epidemiological characteristics of HIV infected Korean: Korea HIV/AIDS Cohort Study

Affiliations
  • 1Department of Preventive Medicine, Hanyang University College of Medicine, Seoul, Korea. bychoi@hanyang.ac.kr
  • 2Institute for Health and Society, Hanyang University, Seoul, Korea.
  • 3Department of Applied Statistics, Yonsei University College of Business and Economics, Seoul, Korea.
  • 4Division of Infectious Disease, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
  • 5Department of Internal Medicine and AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea.
  • 6Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea.
  • 7Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
  • 8Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
  • 9Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
  • 10Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea.
  • 11Division of Viral Disease Research Center for Infectious Disease Research, Korea National Institute of Health, Cheongju, Korea.

Abstract


OBJECTIVES
To manage evidence-based diseases, it is important to identify the characteristics of patients in each country.
METHODS
The Korea HIV/AIDS Cohort Study seeks to identify the epidemiological characteristics of 1,442 Korean individuals with human immunodeficiency virus (HIV) infection (12% of Korean individuals with HIV infection in 2017) who visited 21 university hospitals nationwide. The descriptive statistics were presented using the Korea HIV/AIDS cohort data (2006-2016).
RESULTS
Men accounted for 93.3% of the total number of respondents, and approximately 55.8% of respondents reported having an acute infection symptom. According to the transmission route, infection caused by sexual contact accounted for 94.4%, of which 60.4% were caused by sexual contact with the same sex or both males and females. Participants repeatedly answered the survey to decrease depression and anxiety scores. Of the total participants, 89.1% received antiretroviral therapy (ART). In the initial ART, 95.3% of patients were treated based on the recommendation. The median CD4 T-cell count at the time of diagnosis was 229.5 and improved to 331 after the initial ART. Of the patients, 16.6% and 9.4% had tuberculosis and syphilis, respectively, and 26.7% had pneumocystis pneumonia. In the medical history, sexually transmitted infectious diseases showed the highest prevalence, followed by endocrine diseases. The main reasons for termination were loss to follow-up (29.9%) and withdrawal of consent (18.7%).
CONCLUSIONS
Early diagnosis and ART should be performed at an appropriate time to prevent the development of new infection.

Keyword

HIV; Communicable diseases; AIDS-related opportunistic infections; Antiretroviral therapy highly active

MeSH Terms

AIDS-Related Opportunistic Infections
Anxiety
Cohort Studies*
Communicable Diseases
Depression
Diagnosis
Early Diagnosis
Endocrine System Diseases
Female
Follow-Up Studies
HIV Infections
HIV*
Hospitals, University
Humans
Korea*
Male
Pneumonia, Pneumocystis
Prevalence
Surveys and Questionnaires
Syphilis
T-Lymphocytes
Tuberculosis
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