Epidemiol Health.
2019;41:e2019024. 10.4178/epih.e2019024.
A systematic review and meta-analysis of the genetic characterization of human echinococcosis in Iran, an endemic country
- Siyadatpanah A
- Anvari D
- Emami Zeydi A
- Hosseini S
- Daryani A
- Sarvi S
- Budke CM
- Esmaeelzadeh Dizaji R
- Mohaghegh
- Kohansal M
- Dodangeh S
- Saberi R
- Gholami S
- Affiliations
-
- 1Ferdows Paramedical School, Birjand University of Medical Sciences, Birjand, Iran.
- 2Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.
- 3Department of Parasitology, Student Research Committee, Toxoplasmosis Research Center, Mazandaran University of Medical Science, Sari, Iran.
- 4Department of Microbiology and Immunology, School of Medicine, Iranshahr University of Medical Sciences, Iranshahr, Iran.
- 5Department of Medical-Surgical Nursing, Nasibeh School of Nursing and Midwifery, Mazandaran University of Medical Sciences, Sari, Iran.
- 6Department of Parasitology, Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, Iran. sgholami200@gmail.com
- 7Department of Veterinary Integrative Biosciences, College of Veterinary Medicine Biomedical Sciences, Texas A&M University, College Station, TX , USA.
- 8Department of Poultry Disease, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
- 9Health Sciences Research Center, Department of Laboratory Sciences, School of Paramedical Sciences, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran.
- 10School of Medicine, Bam University of Medical Sciences, Bam, Iran.
- KMID: 2469427
- DOI: http://doi.org/10.4178/epih.e2019024
Abstract
- Human echinococcosis is an infectious disease caused by tapeworms belonging to the species Echinococcus. This parasite has a worldwide distribution and is considered a neglected tropical disease by the World Health Organization. Due to the diversity of Echinococcus spp. hosts, as well as variation in geographical, climatic, and socio-ethnic conditions, the question of the strains or genotypes of Echinococcus spp. that are involved in human infections is important. The aim of this study was to provide a summary of the available data on genotypes of Echinococcus obtained from the Iranian population. Four international databases (PubMed, Scopus, Science Direct, and Web of Science) and 4 Persian databases (Magiran, Scientific Information Database, Iran Medex, and IranDoc) were searched for cross-sectional studies that reported the genotypes of Echinococcus spp. in human echinococcosis cases using molecular methods in Iran through July 2018. The Newcastle-Ottawa Scale was used to assess the quality of the selected studies. A total of 559 cases of human cystic echinococcosis were reported in the 21 included articles. The majority of cases belonged to genotype G1 (89.2%; 95% confidence interval [CI], 80.1 to 95.8), genotype G6 (8.2%; 95% CI, 2.8 to 15.9), and genotype G3 (2.3%; 95% CI, 1.1 to 3.9). Since genotype G1 of Echinococcus appears to be the most prevalent genotype affecting humans in Iran, disease control initiatives aimed at sheep intermediate hosts may be the most beneficial. In addition, educational programs and serological screening in individuals may help reduce the national impact of the disease.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- An Introduction of the Systematic Review and Meta-Analysis
- Critical Appraisal of Systematic Review/Meta-analysis
- Introduction to systematic review and meta-analysis
- Meta-epidemiology
- The effect of antenatal magnesium sulfate on intraventricular hemorrhage in premature infants: a systematic review and meta-analysis
