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The rates of major malformations after gestational exposure to isotretinoin: a systematic review and meta-analysis

Choi EJ, Kim N, Kwak HS, Han HJ, Chun KC, Kim YA, Koh JW, Han JY, Joo SH, Lee JS, Koren G

Objective Isotretinoin is among the most notorious human teratogens, documented originally as causing up to 30% of malformations. This systematic review and meta-analysis aimed to evaluate the rates of major...
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The role of percutaneous neurolysis in lumbar disc herniation: systematic review and meta-analysis

Manchikanti L, Knezevic E, Knezevic NN, Sanapati MR, Kaye AD, Thota S, Hirsch JA

Background: Recalcitrant disc herniation may result in chronic lumbar radiculopathy or sciatica. Fluoroscopically directed epidural injections and other conservative modalities may provide inadequate improvement in some patients. In these cases,...
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A Systematic Review of Virtual Reality Treatment Program on Patients with Post-Traumatic Stress Disorder

Lee W, Cho Y, Kim H

Purpose: The aims of this systematic review were to identify the study protocol of Virtual Reality Therapy (VRT) and review the effect of VRT among patients with Post-Traumatic Stress Disorder...
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Psychosocial support interventions for women with gestational diabetes mellitus: a systematic review

Jung S, Kim Y, Park J, Choi M, Kim S

Purpose: This study aimed to analyze the content and effectiveness of psychosocial support interventions for women with gestational diabetes mellitus (GDM). Methods: The following databases were searched with no limitation of...
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Dengue Virus is Hyperendemic in Nigeria from 2009 to 2020: A Contemporary Systematic Review

Emeribe AU, Abdullahi IN, Isong IK, Emeribe AO, Nwofe JO, Shuaib BI, Gwarzo AM, Usman Y, Sadi M, Umeozuru CM, Dangana A, Egenti BN, Mallam MAB, Emelonye AU, Aminu MS, Yahaya H, Oyewusi S

Backround: Data on Dengue virus (DENV) infection prevalence, geographic distribution and risk factors are necessary to direct appropriate utilization of existing and emerging control strategies. This study aimed to determine...
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Reduction of headache intensity and frequency with maxillary stabilization splint therapy in patients with temporomandibular disorders–headache comorbidity: a systematic review and meta-analysis

Manrriquez SL, Robles K, Pareek K, Besharati A, Enciso R

This systematic review and meta-analysis aimed to analyze the effectiveness of maxillary stabilization splint (SS) therapy to reduce headache (HA) intensity and HA frequency in patients with temporomandibular disorders (TMD)-HA...
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Serum vitamin D status and metabolic syndrome: a systematic review and dose-response meta-analysis

Lee K, Kim J

BACKGROUD/OBJECTIVES: Evidence has suggested an association between serum vitamin D and metabolic syndrome (MetS), but prospective studies are very limited. The objective was to assess the dose-response association between serum...
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A Systematic Review of Non-pharmacological Interventions for Delirium Prevention in Elderly Inpatients

You SB, Lee JH

Purpose: The study was aimed to examine components and provider’s characteristics of non-pharmacological intervention that affect delirium prevention in elderly inpatients. Additional effects on delirium prevention based on identified characteristics...
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Intervention for Married Immigrant Women in Korea: A Systematic Review

Lee SJ, Jin X, Lee S

Purpose: This study aimed to review the intervention programs designed for married immigrant women living in Korea. Methods: A total of 39 articles published from 2010 to 2020 were selected and...
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Clinical, Imaging, and Laboratory Markers of Premanifest Spinocerebellar Ataxia 1, 2, 3, and 6: A Systematic Review

Kim DH, Kim R, Lee JY, Lee KM

Background and Purpose Premanifest mutation carriers with spinocerebellar ataxia (SCA) can exhibit subtle abnormalities before developing ataxia. We summarized the preataxic manifestations of SCA1, -2, -3, and -6, and their...
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Comparative Renal Effects of Dipeptidyl Peptidase-4 Inhibitors and Sodium-Glucose Cotransporter 2 Inhibitors on Individual Outcomes in Patients with Type 2 Diabetes: A Systematic Review and Network Meta-Analysis

Bae JH, Park EG, Kim S, Kim SG, Hahn S, Kim NH

Background: To compare the renal effects of dipeptidyl peptidase-4 (DPP-4) inhibitors and sodium-glucose cotransporter 2 (SGLT2) inhibitors on individual outcomes in patients with type 2 diabetes. Methods: We searched electronic databases...
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Medication Use Review Tools for Community Dwelling Older Patients: A Systematic Review

Park JY, Jun K, Baek YS, Park SY, Lee JY

Background and Objective: The use of potentially inappropriate medications (PIMs) increases the risk of negative health outcomes, including drug-related admissions. Tools for structured medication review have been developed to ensure...
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Birth cohort effects on maternal and child environmental health: a systematic review

Chae J, Kim HK

Purpose: This study aimed to review recent findings from birth cohort studies on maternal and child environmental health. Methods: Birth cohort studies regarding environmental health outcomes for mothers and their children...
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Effects of nursing intervention programs for women with gestational diabetes: a systematic review of randomized controlled trials

Kim J, Chung C

Purpose: This study aimed to identify the effects of nursing intervention programs for women with gestational diabetes mellitus (GDM) through a critical review of recent studies. Methods: Studies related to...
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Laboratory Diagnostic Methods for Clostridioides difficile Infection: the First Systematic Review and Meta-analysis in Korea

Chung HS, Park JS, Shin BM

Background: Various methods are used for the diagnosis of Clostridioides difficile infection (CDI). We systematically analyzed and investigated the performance of current laboratory diagnostic methods for CDI. Methods: We performed systematic...
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The current status of studies of human exposure assessment of microplastics and their health effects: a rapid systematic review

Cho YM, Choi KH

This rapid systematic review aims to summarize studies of human exposure to microplastics (MPs) and their health effects. For the systematic literature review, we separately searched for review articles and...
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Salvage Regimens after Failure of Previous Helicobacter pylori Eradication Therapy: A Systematic Review and Meta-analysis

Yang HJ, Jung HK, Kang SJ, Lee YC, Park SY, Shin CM, Kim SE, Lim HC, Kim JH, Nam SY, Shin WG, Park JM, Choi IJ, Kim JG, Choi M, Korean College of Helicobacter and Upper Gastrointesinal Research

Background/Aims: As antibiotic resistance increases and new first-line therapies emerge, salvage therapies for Helicobacter pylori (H. pylori) eradication failures are becoming more common and complicated. This study aimed to systematically...
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Technical and Clinical Aspects of Diagnostic Single-Balloon Enteroscopy in the First Decade of Use: A Systematic Review and Meta-analysis

Gao Y, Xin L, Zhang YT, Guo XR, Meng QQ, Li ZS, Liao Z

Background/Aims: Single-balloon enteroscopy (SBE) has been widely used in diagnosing small bowel disease. We conducted this study to systematically appraise its technical and clinical performance. Methods: Studies on SBE published by...
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Association between Family Functionality and Depression: A Systematic Review and Meta-Analysis

Guerrero-Muñoz D, Salazar D, Constain V, Perez A, Pineda-Cañar CA, García-Perdomo HA

Background: Different scales have attempted to assess various aspects of family dynamics and structures. Good family function seems to allow for better prognoses for basic diseases and appears to be...
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A systematic review and meta-analysis of flipped learning among university students in Korea: Self-directed learning, learning motivation, efficacy, and learning achievement

Kim SH, Lim JM

Purpose: This study aimed to provide a systematic review and meta-analysis of research on flipped learning effects applied to university students. Methods: The random effect model was applied to 21 papers...
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