Korean J Helicobacter Up Gastrointest Res.  2019 Dec;19(4):220-224. 10.7704/kjhugr.2019.0020.

Helicobacter pylori Eradication after Endoscopic Resection of Gastric Epithelial Neoplasms

Affiliations
  • 1Department of Internal Medicine, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea.
  • 2Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea. harley1333@hanmail.net

Abstract

Endoscopic submucosal dissection is widely accepted as standard treatment for early gastric cancer; however, long-term management of metachronous gastric cancer after endoscopic resection is an important issue that is gaining much attention. Several prospective and retrospective studies have reported that Helicobacter pylori (H. pylori) eradication can reduce the risk of metachronous gastric cancer after endoscopic resection. Although there is lack of sufficient data regarding this subject, a few studies have reported histologically proven improvement in atrophic gastritis and intestinal metaplasia following H. pylori eradication in patients undergoing endoscopic resection. Therefore, treatment for H. pylori eradication should be considered in this patient population to reduce the incidence of metachronous gastric cancer and improve long-term outcomes.(

Keyword

Helicobacter pylori; Neoplasms, second primary; Stomach neoplasms; Therapeutics

MeSH Terms

Gastritis, Atrophic
Helicobacter pylori*
Helicobacter*
Humans
Incidence
Metaplasia
Neoplasms, Glandular and Epithelial*
Neoplasms, Second Primary
Prospective Studies
Retrospective Studies
Stomach Neoplasms
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