Korean J Head Neck Oncol.  2019 Nov;35(2):39-43. 10.21593/kjhno/2019.35.2.39.

A Case of an Isolated Peripheral Giant Cell Granuloma in the Parotid Gland

• Kim SJ
• Yun JH
• Park S
• Kim HS

• KMID: 2469234
• DOI: http://doi.org/10.21593/kjhno/2019.35.2.39

Abstract

Peripheral giant cell granuloma (PGCG) is an benign non-neoplastic lesion most commonly occurring in oral cavity but extraoral PGCG is extremely rare. Recently, we experienced a case of an isolated PGCG in the parotid gland in 59-year-old man. FNAB findings and radiologic findings including CT and US were suggestive of Warthin's tumor. Partial parotidectomy was performed. Pathologic findings showed fibrillar connective tissue stroma with spindled, ovoid, and round histiocytes-like cells mixed with uneven multinuclear giant cells, small capillaries, hemorrhage, hemosiderin-laden macrophages, and necrosis which were consistent with giant cell granuloma. We report a case of an PGCG in parotid with a review of literature.

Keyword

Peripheral giant cell granuloma; PGCG; Parotid gland

MeSH Terms

Capillaries
Connective Tissue
Giant Cells
Granuloma, Giant Cell*
Hemorrhage
Humans
Macrophages
Middle Aged
Mouth
Necrosis
Parotid Gland*