J Korean Soc Radiol.  2020 Jan;81(1):219-224. 10.3348/jksr.2020.81.1.219.

Inflammatory Endobronchial Myofibroblastic Tumor: A Case Report

• Nam SW
• Jeong YJ
• Lee G
• Lee JW
• Eom JS
• Cho JS
• Park WY
• Park SM

• KMID: 2469197
• DOI: http://doi.org/10.3348/jksr.2020.81.1.219

Abstract

Inflammatory myofibroblastic tumor is a rare benign lesion that accounts for 0.04-1% of all lung tumors and usually appears as a solitary pulmonary nodule or mass. Here, we report the case of an endobronchial inflammatory myofibroblastic tumor in a 21-year-old man with a focus on the imaging findings and a review of previous literature.

MeSH Terms

Bronchial Neoplasms
Humans
Lung
Multidetector Computed Tomography
Myofibroblasts*
Solitary Pulmonary Nodule
Young Adult

Figure

• 

  Fig. 1 A 21-year-old-man with an endobronchial inflammatory myofibroblastic tumor A. Posteroanterior and lateral chest radiographs show a well-defined, lobulated mass in the lower left lung lobe (arrows). B. Axial and coronal CT images show a 5 cm wide, well-defined, lobulated or branching mass with a small endobronchial portion (iceberg lesion, arrows) in the superior segment of the left lower lung lobe. C. Axial images of pre-contrast and contrast-enhanced CT scan show mild enhancement of the tumor. D. Bronchoscopy shows a yellowish-white endobronchial mass obstructing the superior segmental bronchus of the left lower lung lobe. E. Histological examination (H&E, × 100) reveals a proliferation of spindle cells (arrows) showing fibroblastic and myofibroblastic differentiation and multifocal infiltrations of lymphoplasma cells (arrowheads) in a myxoid stroma. Immunostaining for vimentin (× 400) and smooth muscle actin (× 400) show strong positive staining on the neoplastic cells. H&E = hematoxylin and eosin stain

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