J Rhinol.  2020 May;27(1):67-71. 10.18787/jr.2020.00318.

Inflammatory Myofibroblastic Tumor of Nasal Septum after Septoplasty: A Case Report

• Oh J
• Choi JY

• KMID: 2502799
• DOI: http://doi.org/10.18787/jr.2020.00318

Abstract

Inflammatory myofibroblastic tumor is an uncommon tumor composed of myoblasts and various types of inflammatory infiltrates. Inflammatory myofibroblastic tumor is most common in the lungs but can be rarely found in the nasal cavity. Inflammatory myofibroblastic tumor is a rare entity that represents a diverse histologic pattern that can mimic malignant tumors. We report a case of inflammatory myofibroblastic tumor of the nasal septum in a 45-year-old man who presented with a tumor-like lesion of the nasal septum after two rounds of septoplasty.

Keyword

Nasal septum; Neoplasms; Inflammation; 비중격; 염증성; 종양

Figure

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  Fig. 1. Nasal endoscopic finding shows both nasal cavity obstructed by septal mass.

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  Fig. 2. Nasal endoscopic findings show a septal perforation (A) and a smooth-surfaced, pinkish-colored mass lesion on cephalic area of nasal septum (B).

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  Fig. 3. PNS CT demonstrates a heterogeneous enhanced soft tissue mass at nasal dorsum and septum that extends to inferior turbinate. The axial view (A) and coronal view (B).

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  Fig. 4. Preoperative MRI finding. A: T1-weighted axial image demonstrates a heterogeneous enhanced mass with moderate signal intensity at nasal dorsum and septum. B: T2-weighted axial image demonstrates a heterogeneous enhanced mass with low signal intensity at nasal dorsum and septum. C: T1-weighted enhanced coronal image shows relatively well-marginated mass with high intensity signal at the septum.

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  Fig. 5. Tumor is presented as a firm, well-circumscribed nodular mass with a various cut surface.

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  Fig. 6. Tumor is full of spindle cell arranged in fascicular pattern. Proliferation of fibrocollagenous tissue mixed with inflammatory cells including eosinophils, neutrophils and lymphocytes (H & E, ×100)(A). Histologic finding shows low cellurarity, lack of cellular atypia and dense inflammatory infiltrates (H & E, ×400)(B).

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  Fig. 7. The frontal and lateral views of patient shows no prominent saddle nose deformity after the operation.

Reference

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