Korean J Urol.  2006 Aug;47(8):910-912. 10.4111/kju.2006.47.8.910.

Inflammatory Myofibroblastic Tumor of Kidney

• Lee DH
• Soh BH
• Lee SH
• Oh YT
• Lee YS
• Rha KH

• KMID: 2294124
• DOI: http://doi.org/10.4111/kju.2006.47.8.910

Abstract

Inflammatory myofibroblastic tumor (IMT) is a very rare benign mass lesion. Inflammatory myofibroblastic tumor of genitourinary tract most frequently involves the urinary bladder. Renal inflammatory myofibroblastic tumor is rare. Renal inflammatory myofibroblastic tumor usually remain asymtomatic until the tumor occurs obstructive uropathy. We experienced a case of right renal inflammatory myofibroblastic tumor.

Keyword

Myofibroma; Inflammatory pseudotumor; Kidney

MeSH Terms

Granuloma, Plasma Cell
Kidney*
Myofibroblasts*
Myofibroma
Urinary Bladder

Figure

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  Fig. 1 Contrast enhanced computed tomography demonstrates a 5×5cm sized solid mass with poor enhancement on right kidney upper pole and a 2cm sized cystic lesion on uncinate process of pancreas.

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  Fig. 2 Contrast enhanced computed tomography demonstrates multiple gallbladder stones with mild gallbladder wall thickening and right pelvis dilatation.

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  Fig. 3 Magnetic resonance imaging demonstrates solid mass in the renal pelvicalyceal system, upper portion of the Rt kidney with secondary cystic change of upper calyceal system and pancreas head with internal septation and suspicious mural nodule and multiple stones in the gallbladder.

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  Fig. 4 (A) Gross feature in right kidney: multilobulated solid bright yellow mass, measuring 6.5×4.5cm which is located at the mid to upper pole with adjacent renal calyceal dilatation. (B) Histologic features in right kidney: presence of compact spindle cell (H-E stain).

Reference

1. Karnak I, Senocak ME, Ciftci AO, Caglar M, Bingol-Kologlu M, Tanyel FC, et al. Inflammatory myofibroblastic tumor in children: diagnosis and treatment. J Pediatr Surg. 2001. 36:908–912.

2. Coffin CM, Watterson J, Priest JR, Dehner LP. Extrapulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor): a clinicopathologic and immunohistochemical study of 84 cases. Am J Surg Pathol. 1995. 19:859–872.

3. Kapusta LR, Weiss MA, Ramsay J, Lopez-Beltran A, Srigley JR. Inflammatory myofibroblastic tumors of the kidney: a clinicopathologic and immunohistochemical study of 12 cases. Am J Surg Pathol. 2003. 27:658–666.

4. Choi BY, Kim WS, Cheon JE, Kim IO, Kim CJ, Yeon KM. Inflammatory myofibroblastic tumour of the liver in a child: CT and MR findings. Pediatr Radiol. 2003. 33:30–33.

5. Arber DA, Kamel OW, van de Rijn M, Davis RE, Medeiros LJ, Jaffe ES, et al. Frequent presence of the Epstein Barr virus in inflammatory pseudotumor. Hum Pathol. 1995. 26:1093–1098.

6. Gomez-Roman JJ, Sanchez-Velasco P, Ocejo-Vinyals G, Hernandez-Nieto E, Leyva-Cobian F, Val-Bernal JF. Human herpesvirus-8 genes are expressed in pulmonary inflammatory myofibroblastic tumor. Am J Surg Pathol. 2001. 25:624–629.

7. Lee SH, Fang YC, Luo JP, Kuo HI, Chen HC. Inflammatory pseudotumour associated with chronic persistent Eikenella corrodens infection: a case report and brief review. J Clin Pathol. 2003. 56:868–870.

8. Kempson RL, Fletcher CD, Evans HL, Hendrickson MR, Sibley RK. Fibrous and myofibroblastic tumors. Atlas of tumor pathology: tumors of the soft tissues. 2001. Washington: Armed Forces Institute of Pathology;83–86.

9. Sugimoto K, Hayashi T, Imanishi M, Kadowaki T, Kurita T. A case of inflammatory pseudotumor of renal pelvis showing a complete response to antibiotics. Hinyokika Kiyo. 2004. 50:629–631.

10. Williams ME, Longmaid EE, Trey G, Federman M, Crosson AW. Renal failure resulting from infiltration by inflammatory myofibroblastic tumor responsive to corticosteroid therapy. Am J Kidney Dis. 1998. 31:E5.