Maxillofac Plast Reconstr Surg.  2019 ;41(1):16. 10.1186/s40902-019-0199-z.

Retrospective comparative clinical study for silk mat application into extraction socket

• Kim JW
• Jo YY
• Kim JY
• Oh JH
• Yang BE
• Kim SG

• KMID: 2468964
• DOI: http://doi.org/10.1186/s40902-019-0199-z

Abstract

BACKGROUND
Silk mats have been approved for clinical trials by the Korean Food and Drug Administration as membranes for guided tissue regeneration (GTR). In this study, silk mat application was compared to high-density polytetrafluoroethylene (dPTFE) membrane application or no membrane group.
METHODS
To compare the silk mat group to the dPTFE group or the no membrane group, a retrospective sample collection was conducted. Bony defects were measured at the time of extraction (T0) and then at 3"‰months (T1) and 6"‰months after extraction (T2) on a digital panoramic view. Bone gain (BG) was calculated by subtracting from the bony defect at T0 to the bony defect at each follow-up.
RESULTS
The BG at T2 was 2.44"‰±"‰2.49"‰mm, 4.18"‰±"‰1.80"‰mm, and 4.24"‰±"‰2.05"‰mm in the no membrane group, silk mat group, and dPTFE group, respectively. Both membrane groups had significantly higher BG than BG in the no membrane group at T2 (P"‰<"‰0.05).
CONCLUSIONS
Both membrane groups showed higher BG than the no membrane group.

Keyword

Guided tissue regeneration; Silk mat; Polytetrafluoroethylene; Probing depth; Bone gain

MeSH Terms

Clinical Study*
Follow-Up Studies
Guided Tissue Regeneration
Membranes
Polytetrafluoroethylene
Retrospective Studies*
Silk*
United States Food and Drug Administration
Polytetrafluoroethylene
Silk