Korean J Otorhinolaryngol-Head Neck Surg.  2019 Nov;62(11):657-662. 10.3342/kjorl-hns.2018.00850.

Two Cases of Localized Myeloperoxidase-Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Manifested with Intractable Otitis Media

Affiliations
  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. wonho.chung@samsung.com

Abstract

Localized form of myeloperoxidase-antineutrophil cytoplasmic antibody-associated vasculitis (MPO-AAV) in the ear is a rare disease. It manifests as a sudden otalgia with hearing loss accompanied by dizziness and facial nerve palsy. Early diagnosis and treatment with immunosuppressive agents are important to prevent the irreversible progression of sensorineural hearing loss. However, it is hard to diagnose AAV because it can be confused with other common otologic disease, such as acute otitis media or middle ear effusion with labyrinthitis. Here, we report two cases of localized form of MPO-AAV manifesting otologic symptoms that have been properly diagnosed and treated with steroid and immunosuppressant.

Keyword

Antibodies; Antineutrophil cytoplasmic; Otitis media; Myeloperoxidases

MeSH Terms

Antibodies
Cytoplasm*
Dizziness
Ear
Ear Diseases
Ear, Inner
Earache
Early Diagnosis
Facial Nerve
Hearing Loss
Hearing Loss, Sensorineural
Immunosuppressive Agents
Labyrinthitis
Otitis Media with Effusion
Otitis Media*
Otitis*
Paralysis
Rare Diseases
Vasculitis*
Antibodies
Immunosuppressive Agents
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