Neonatal Med.  2019 Nov;26(4):229-232. 10.5385/nm.2019.26.4.229.

Successful Treatment of Neonatal Herpes Simplex Infection Presenting as Fulminant Hepatitis with Acyclovir and Peritoneal Dialysis

Affiliations
  • 1Department of Pediatrics, Ajou University Hospital, Ajou University School of Medicine, Suwon, Korea. neopedlee@gmail.com

Abstract

Disseminated neonatal herpes simplex virus (HSV) infection is a severe disease with a high mortality rate. Here, we report the patient presented with fulminant hepatic failure secondary to HSV infection followed by renal failure without any mucocutaneous symptoms. The patient recovered after treatment with acyclovir and peritoneal dialysis. This is the first known case of a patient in Korea who survived disseminated HSV infection with fulminant liver failure followed by renal failure without undergoing liver transplantation.

Keyword

Infant, newborn; Fulminant hepatitis; Liver failure; Herpes simplex

MeSH Terms

Acyclovir*
Hepatitis*
Herpes Simplex*
Humans
Infant, Newborn
Korea
Liver Failure
Liver Failure, Acute
Liver Transplantation
Mortality
Peritoneal Dialysis*
Renal Insufficiency
Simplexvirus
Acyclovir
Full Text Links
  • NM
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
    DB Error: unknown error