J Korean Neurol Assoc.
2007 Aug;25(3):393-397.
Relapsing Herpes Simplex Encephalitis
- Affiliations
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- 1Department of Neurology, college of Medicine, Hanyang University, Seoul, Korea. kimjuhan@hanyang.ac.kr
Abstract
- Herpes simplex encephalitis (HSE) is the most common type of viral encephalitis and a fourteen day administration of acyclovir is well-known as the treatment of choice for HSE. Occasionally HSE relapses, but rarely with acyclovir treatment. We report a case of relapsing HSE after treatment with acyclovir for 14 days. Our case suggests that patients with progressive high signal intensities in diffusion-weighted brain MRIs might need longer antiviral therapy over 14 days for preventing the relapse of herpes simplex encephalitis.
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