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Differences in Dysphagia between Patients with Stroke or Amyotrophic Lateral Sclerosis

Lee JY, Park YC, Lee J, Park J, Oh KW, Kim SH, Kim MJ

Objective: Dysphagia is a common symptom of stroke and affects 23–50% of such patients. In addition, bulbar involvement, which causes dysphagia, is the primary initial symptom in approximately 25–30% of...
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Intussusception in Neonates: Clinical Characteristics of Eight Cases in a Single Center

Ahn Yg, Lim G, Hwang EH, Oh KW, Cho MJ

Purpose: Intussusception is the most common cause of bowel obstruction in children; however, it is rarely diagnosed in newborn infants. This study aimed to describe the clinical features of intussusception...
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Clinical Characteristics of Korean Juvenile Amyotrophic Lateral Sclerosis

Lee S, Park J, Oh KW, Kim SH

Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive motor neuron degeneration with phenotypic heterogeneity, including age at onset. Juvenile ALS (JALS) includes ALS patients aged less...
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Hepatic Subcapsular Hematoma with Different Clinical Features in Two Neonates

Oh Y, Lim G, Oh KW

The liver of a newborn is vulnerable to damage during the process of delivery or on external manipu lation. Although hepatic subcapsular hematoma occurs relatively commonly in the perinatal period,...
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Severe Late-onset Anemia Associated with Rhesus D Alloimmunization

Jeon J, Lim G, Oh KW

Rhesus D (RhD) alloimmunization is the most severe cause of hemolytic disease of the fetus and newborn (HDFN). However, owing to medical advances, pediatricians are likely to encounter only a...
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Serum Transferrin Predicts New-Onset Type 2 Diabetes in Koreans: A 4-Year Retrospective Longitudinal Study

Kim JD, Lim DM, Park KY, Park SE, Rhee EJ, Park CY, Lee WY, Oh KW

Background: It is well known that high serum ferritin, a marker of iron storage, predicts incident type 2 diabetes. Limited information is available on the association between transferrin, another marker...
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Post-Traumatic Guillain-Barre Syndrome

Jo SH, Lee J, Lee J, Kim JH, Park J, Kim SH, Oh Kw

Guillain-Barre syndrome (GBS) is acute inflammatory demyelinating polyradiculoneuropathy, which is often related to post-infectious etiology. However, GBS has also been reported to be caused by non-infectious factors such as trauma....
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A Therapeutic Strategy for Alzheimer's Disease Focused on Immune-inflammatory Modulation

Kim SH, Noh MY, Kim HJ, Oh KW, Park J, Lee S, Moon Y, Kim YE, Bae JS, Jin HK, K-ARPI

Alzheimer's disease (AD), the most common form of dementia, has emerged as a major global public health challenge. However, the complexity of AD in its biological, genetic, and clinical aspects...
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Data resource profile: oral examination of the Korea National Health and Nutrition Examination Survey

Woo GJ, Lee HR, Kim Y, Kim HJ, Park DY, Kim JB, Oh KW, Choi YH

OBJECTIVES: The Korea National Health and Nutrition Examination Survey (KNHANES) is a national surveillance system that has been assessing the health and nutritional status of Koreans since 1998. Based on...
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A De Novo RAPGEF2 Variant Identified in a Sporadic Amyotrophic Lateral Sclerosis Patient Impairs Microtubule Stability and Axonal Mitochondria Distribution

Heo K, Lim SM, Nahm M, Kim YE, Oh KW, Park HT, Ki CS, Kim SH, Lee S

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that is frequently linked to microtubule abnormalities and mitochondrial trafficking defects. Whole exome sequencing (WES) of patient-parent trios has proven to...
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Deficiency of Sphingosine-1-Phosphate Reduces the Expression of Prohibitin and Causes β-Cell Impairment via Mitochondrial Dysregulation

Hong SW, Lee J, Kwon H, Park SE, Rhee EJ, Park CY, Oh KW, Park SW, Lee WY

BACKGROUND: Emerging evidence suggests that sphingolipids may be involved in type 2 diabetes. However, the exact signaling defect through which disordered sphingolipid metabolism induces β-cell dysfunction remains unknown. The current...
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Cocaine- and Amphetamine-Regulated Transcript (CART) Peptide Plays Critical Role in Psychostimulant-Induced Depression

Meng Q, Kim HC, Oh S, Lee YM, Hu Z, Oh KW

Cocaine- and amphetamine-regulated transcript (CART) peptide is a widely distributed neurotransmitter expressed in the central nervous systems. Previously, several reports demonstrated that nucleus accumbal-injected CART peptide positively modulated behavioral sensitization...
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Subacute Combined Degeneration and Pulmonary Thromboembolism due to Nitrous Oxide Inhalation for Recreational Use

Kim SJ, Lee J, Kim YS, Oh KW, Kim SH, Park J

No abstract available.
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Sleep-Aids Derived from Natural Products

Hu Z, Oh S, Ha TW, Hong JT, Oh KW

Although drugs such as barbiturates and benzodiazepines are often used for the treatment of insomnia, they are associated with various side effects such as habituations, tolerance and addiction. Alternatively, natural...
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Administration of Alpha(s1)-Casein Hydrolysate Increases Sleep and Modulates GABA(A) Receptor Subunit Expression

Yayeh T, Leem YH, Kim KM, Jung JC, Schwarz J, Oh KW, Oh S

Sleep is the most basic and essential physiological requirement for mental health, and sleep disorders pose potential risks of metabolic and neurodegenerative diseases. Tryptic hydrolysate of α(S1)-casein (α(S1)-CH) has been...
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Hypothermia Inhibits Endothelium-Independent Vascular Contractility via Rho-kinase Inhibition

Chung YH, Oh KW, Kim ST, Park ES, Je HD, Yoon HJ, Sohn UD, Jeong JH, La HO

The present study was undertaken to investigate the influence of hypothermia on endothelium-independent vascular smooth muscle contractility and to determine the mechanism underlying the relaxation. Denuded aortic rings from male...
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Pioglitazone Attenuates Palmitate-Induced Inflammation and Endoplasmic Reticulum Stress in Pancreatic β-Cells

Hong SW, Lee J, Cho JH, Kwon H, Park SE, Rhee EJ, Park CY, Oh KW, Park SW, Lee WY

BACKGROUND: The nuclear receptor peroxisome proliferator-activator gamma (PPARγ) is a useful therapeutic target for obesity and diabetes, but its role in protecting β-cell function and viability is unclear. METHODS: To identify...
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The Association between Persistent Hypertriglyceridemia and the Risk of Diabetes Development: The Kangbuk Samsung Health Study

Kwon YH, Kim SK, Cho JH, Kwon H, Park SE, Oh HG, Park CY, Lee WY, Oh KW, Park SW, Rhee EJ

BACKGROUND: Hypertriglyceridemia is known to have an association with increased risks of insulin resistance and diabetes. The aim of this study was to investigate the risk of diabetes mellitus, according...
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Staphylococcus capitis Induced Late-onset Sepsis in Very Low Birth Weight Infants

Kim I, Lim G, Hwang EH, Oh KW, Jeong J

OBJECTIVE: To determine the causative organisms of late-onset sepsis (LOS) and describe LOS induced by Staphylococcus capitis (S. capitis) in very low birth weight infants (VLBWI). METHODS: The medical records of...
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Changes in Body Composition According to Age and Sex among Young Non-Diabetic Korean Adults: the Kangbuk Samsung Health Study

Kim SK, Kwon YH, Cho JH, Lee DY, Park SE, Oh HG, Park CY, Lee WY, Oh KW, Park SW, Rhee EJ

BACKGROUND: Age-related decreases in lean mass represent a serious health problem. We aimed to analyze the risks of rapid decreases in lean mass by age and sex in relatively young...
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