Pediatr Infect Vaccine.  2019 Dec;26(3):188-193. 10.14776/piv.2019.26.e19.

Cerebral Venous Sinus Thrombosis with Meningitis and Septicemia due to Haemophilus influenzae Type f in an Immunocompetent Child

• Han H
• Lee KJ
• Yu HJ

• KMID: 2466463
• DOI: http://doi.org/10.14776/piv.2019.26.e19

Abstract

Since the implementation of conjugate Haemophilus influenzae serotype b (Hib) vaccine, the rate of infections caused by Hib has dramatically decreased, and the proportion of infections caused by non-type b H. influenzae has increased. Cerebral venous sinus thrombosis (CVST) is rare; however, it should be considered as a potential complication of bacterial meningitis. Herein, we report about a child who developed CVST after being diagnosed with H. influenzae serotype f meningitis.

Keyword

Meningitis, haemophilus; Sinus thrombosis, intracranial; Central Nervous system infections; Cerebrospinal fluid; Bacteremia

MeSH Terms

Bacteremia
Central Nervous System Infections
Cerebrospinal Fluid
Child*
Haemophilus influenzae type b
Haemophilus influenzae*
Haemophilus*
Humans
Influenza, Human
Meningitis*
Meningitis, Bacterial
Meningitis, Haemophilus
Sepsis*
Serogroup
Sinus Thrombosis, Intracranial*

Figure

• 

  Fig. 1 Non-contrast-enhanced computed tomography performed on the 1st hospital day showed a high-density lesion noted in right transverse-sigmoid sinus area (arrow) (A). Brain magnetic resonance images were taken on the 5th hospital day (B-D). Distended right side transverse-sigmoid sinus was hyperintense on axial contrast-enhanced T1-weighted image (B) and hypointense on susceptibility-weighted image (C). Right side transverse and sigmoid sinus obstruction is seen on venography (D).

• 

  Fig. 2 The follow-up brain magnetic resonance images performed 2 months after the initial study. The aforementioned hyperintense lesion appears to have resolved on contrast-enhanced T1-weighted image (A) and the hypointense lesion has almost disappeared on susceptibility-weighted image (B). Recanalization of thrombosis was seen in right side transverse and sigmoid sinus on venography (C).

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