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[ 64 Cu]Cu-Albumin Clearance Imaging to Evaluate Lymphatic Efflux of Cerebrospinal Space Fluid in Mouse Model

Sarker A, Suh M, Choi Y, Park JY, Kwon S, Kim H, Lee E, Seo H, Lee YS, Lee DS

Purpose Clearance of brain waste in the cerebrospinal fluid (CSF) through the meningeal lymphatic vessels (mLV) has been evaluated mostly through the fluorescent imaging which has inherent limitations in the...
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Pediatric Minor Traumatic Brain Injury : Growing Skull Fracture, Traumatic Cerebrospinal Fluid Leakage, Concussion

Choi JI, Kim SD

Traumatic brain injury (TBI) is a major public health issue that causes significant morbidity and mortality in the pediatric population. Pediatric minor TBIs are the most common and are widely...
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Recurrent L3 Chordoma Presented as Intradural Extramedullary Mass With Distant Metastasis: A Case Report

Jang SJ, Han N, Hong EK, Gwak HS

Here, we report a rare case of L3 chordoma progressed to an intradural extramedullary (IDEM) mass and distant metastasis to the fascia lata. A 64-year old female patient presented to...
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Risk factors associated with repeated epidural blood patches using autologous blood

Oh AR, Park J, Jeong JS, Lee JY, Choi JW, Kim H, Sim WS

Background: An epidural blood patch (EBP) is a procedure to treat intracranial hypotension that does not respond to conservative treatment. EBPs are commonly repeated when the symptoms persist. In this...
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Bioinformatics Analysis of Autophagy and Mitophagy Markers Associated with Delayed Cerebral Ischemia Following Subarachnoid Hemorrhage

Youn DH, Kim BJ, Hong EP, Jeon JP, on behalf of the first Korean Stroke Genetics Association Research

Objective : To evaluate the interactions among differentially expressed autophagy and mitophagy markers in subarachnoid hemorrhage (SAH) patients with delayed cerebral ischemia (DCI). Methods : The expression data of autophagy and...
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Promising candidate cerebrospinal fluid biomarkers of seizure disorder, infection, inflammation, tumor, and traumatic brain injury in pediatric patients

Kim SH, Chae SA

Cerebrospinal fluid (CSF) is a dynamic metabolically active body fluid that has many important roles and is commonly analyzed in pediatric patients, mainly to diagnose central nervous system infection and...
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Heavily T2-Weighted Magnetic Resonance Myelography as a Safe Cerebrospinal Fluid Leakage Detection Modality for Nontraumatic Subdural Hematoma

An S, Jeong HG, Seo D, Jo H, Lee SU, Bang JS, Oh CW, Kim T

Objective : Nontraumatic subdural hematoma (SDH) is a common disease, and spinal cerebrospinal fluid (CSF) leakage is a possible etiology of unknown significance, which is commonly investigated by several invasive...
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Delayed Tension Pneumocephalus Following Intraoperative Cerebrospinal Fluid Leakage Repair

Park JY, Kim H, Jung T, Kim JK

Tension pneumocephalus is a rare complication of endoscopic sinus surgery (ESS) that may lead to rapid neurologic deterioration. Symptoms typically develop within the first postoperative week after enough air has...
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A Case of Penetrating Brain Injury Followed by Delayed Cerebrospinal Fluid Leakage

Kim TG, Sin EG

Although penetrating brain injury is rare, it is associated with high morbidity and mortality. In several studies, even if very few patients arrive at the hospital alive, half of them...
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Reliability of Early Ambulation after Intradural Spine Surgery : Risk Factors and a Preventive Method for Cerebrospinal Fluid Leak Related Complications

Lee S, Cho DC, Kim KT, Lee YS, Rhim SC, Park JH

Objective : Cerebrospinal fluid leakage related complications (CLC) occasionally occur after intradural spinal surgery. We sought to investigate the effectiveness of early ambulation after intradural spinal surgery and analyze the...
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A New Look on an Old Issue: Comprehensive Review of Neurotransmitter Studies in Cerebrospinal Fluid of Patients with Schizophrenia and Antipsychotic Effect on Monoamine’s Metabolism

Gasnier M, Ellul P, Plaze M, Ahad PA

Neurotransmitters metabolism has a key role in the physiopathology of schizophrenia as demonstrated by studies measuring monoamine metabolites in patient’s cerebrospinal fluid (CSF) since the beginning of the antipsychotic use....
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Patterns of Cerebrospinal Fluid Biomarkers and Amyloid Positron Emission Tomography in a Patient with Cerebral Amyloid Angiopathy-Related Inflammation

Kim JY, Jo S, Park YJ, Jung HJ, Koo YS, Lee JH

Cerebral amyloid angiopathy-related inflammation (CAA-RI) is a distinct subset of cerebral amyloid angiopathy characterized by the auto-inflammatory response to amyloid-laden small arteries of cerebral cortex and leptomeninges. Clinical features include...
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Cerebrospinal Fluid Profiles and Their Changes after Intraventricular Chemotherapy as Prognostic or Predictive Markers for Patients with Leptomeningeal Carcinomatosis

Kwon JW, Shim Y, Gwak HS, Park EY, Joo J, Yoo H, Shin SH

Objective : Here, we evaluated whether cerebrospinal fluid (CSF) profiles and their changes after intraventricular chemotherapy for leptomeningeal carcinomatosis (LMC) could predict the treatment response or be prognostic for patient...
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Multi-Layer Onlay Graft Using Hydroxyapatite Cement Placement without Cerebrospinal Fluid Diversion for Endoscopic Skull Base Reconstruction

Kim YH, Kang H, Dho YS, Hwang K, Joo JD, Kim YH

Objective : The skull base reconstruction step, which prevents cerebrospinal fluid (CSF) leakage, is one of the most challenging steps in endoscopic skull base surgery (ESS). The purpose of this...
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High Levels of IL-8 and MCP-1 in Cerebrospinal Fluid of COVID-19 Patients with Cerebrovascular Disease

Guartazaca-Guerrero S, Rodríguez-Morales J, Rizo-Téllez SA, Solleiro-Villavicencio H, Hernández-Valencia AF, Carrillo-Ruiz JD, Escobedo G, Méndez-García LA

  • KMID: 2517478
  • Exp Neurobiol.
  • 2021 Jun;30(3):256-261.
  • doi: 10.5607/en21009
The coronavirus family has tropism for the Central Nervous System (CNS), however, there is no solid evidence demonstrating that the neurological effects of COVID-19 result from direct viral infection or...
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Novel Tie Method for the Fixation of a Brain Infusion Cannula in a Murine Model

Mun SK, Chang M

Although brain infusion cannula is a good method to deliver compounds directly into the brain, fixation of the brain infusion cannula is essential for successful delivery. Dental cements and adhesive...
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Systematic Review and Meta-Analysis of Antibiotic-Impregnated Shunt Catheters on Anti-Infective Effect of Hydrocephalus Shunt

Zhou Wx, Hou Wb, Zhou C, Yin Yx, Lu St, Liu G, Fang Y, Li Jw, Wang Y, Liu Ah, Zhang Hj

Objective : Shunt infection is a common complication while treating hydrocephalus. The antibiotic-impregnated shunt catheter (AISC) was designed to reduce shunt infection rate. A meta-analysis was conducted to study the...
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A Case of a 50-Year Old Women with Cerebrospinal Fluid Rhinorrhea and Right Nasal Cavity Mass

Park HS, Mo JH, Chung YJ

A 50-year-old woman visited the hospital with persistent watery rhinorrhea which she had for 2 months. Endoscopic examination revealed a mass in the right nasal cavity and rdiological findings revealed...
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Cerebrospinal fluid flow in normal beagle dogs analyzed using magnetic resonance imaging

Cho H, Kim Y, Hong S, Choi H

Background: Diseases related to cerebrospinal fluid flow, such as hydrocephalus, syringomyelia, and Chiari malformation, are often found in small dogs. Although studies in human medicine have revealed a correlation with...
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A Case of Petrous Apex Meningocele: Unusual Presentation of Cerebrospinal Fluid Leak Following Adenoidectomy

Kim BK, Heo Y, Kong DS, Hong SD

Cerebrospinal fluid (CSF) leak is possible and can be a cause of recurrent bacterial meningitis. Petrous apex meningocele (PAM) is mostly asymptomatic and is often found during incidental imaging tests....
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