J Gynecol Oncol.  2020 Jan;31(1):e18. 10.3802/jgo.2020.31.e18.

Japan Society of Gynecologic Oncology 2018 guidelines for treatment of uterine body neoplasms

Affiliations
  • 1Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan
  • 2Department of Obstetrics and Gynecology, Tokai University School of Medicine, Kanagawa, Japan
  • 3Department of Obstetrics and Gynecology, Faculty of Medicine, Yamagata University, Yamagata, Japan
  • 4Department of Obstetrics and Gynecology, Tokyo Women's Medical University, Tokyo, Japan
  • 5Department of Obstetrics and Gynecology, Kyorin University Faculty of Medicine, Tokyo, Japan
  • 6Department of Gynecology, Otaru General Hospital, Hokkaido, Japan
  • 7Department of Obstetrics and Gynecology, Faculty of Medicine, Kagoshima University, Kagoshima, Japan
  • 8Department of Gynecology, Miyagi Cancer Center, Miyagi, Japan
  • 9Department of Obstetrics and Gynecology, Dokkyo Medical University, Tochigi, Japan
  • 10Department of Obstetrics and Gynecology, Jichi Medical University, Tochigi, Japan
  • 11Department of Obstetrics and Gynecology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

Abstract

The Fourth Edition of the Guidelines for Treatment of Uterine Body Neoplasm was published in 2018. These guidelines include 9 chapters: 1. Overview of the guidelines, 2. Initial treatment for endometrial cancer, 3. Postoperative adjuvant therapy for endometrial cancer, 4. Post-treatment surveillance for endometrial cancer, 5. Treatment for advanced or recurrent endometrial cancer, 6. Fertility-sparing therapy, 7. Treatment of uterine carcinosarcoma and uterine sarcoma, 8. Treatment of trophoblastic disease, 9. Document collection; and nine algorithms: 1-3. Initial treatment of endometrial cancer, 4. Postoperative adjuvant treatment for endometrial cancer, 5. Treatment of recurrent endometrial cancer, 6. Fertility-sparing therapy, 7. Treatment for uterine carcinosarcoma, 8. Treatment for uterine sarcoma, 9. Treatment for choriocarcinoma. Each chapter includes overviews and clinical questions, and recommendations, objectives, explanation, and references are provided for each clinical question. This revision has no major changes compared to the 3rd edition, but does have some differences: 1) an explanation of the recommendation decision process and conflict of interest considerations have been added in the overview, 2) nurses, pharmacists and patients participated in creation of the guidelines, in addition to physicians, 3) the approach to evidence collection is listed at the end of the guidelines, and 4) for clinical questions that lack evidence or clinical validation, the opinion of the Guidelines Committee is given as a "Recommendations for tomorrow".

Keyword

Clinical Practice Guideline; Endometrial Cancer; Treatment; Gestational Trophoblastic Disease; Uterine Sarcoma

MeSH Terms

Carcinosarcoma
Choriocarcinoma
Conflict of Interest
Endometrial Neoplasms
Female
Gestational Trophoblastic Disease
Humans
Japan*
Pharmacists
Pregnancy
Sarcoma
Trophoblasts
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