J Korean Soc Radiol.  2019 Nov;80(6):1241-1246. 10.3348/jksr.2019.80.6.1241.

Intractable Headache Related to Intraventricular Glioblastoma: A Case Report and Literature Review

• Han DY
• Lee KM
• Kim HG
• Kim EJ

• KMID: 2464921
• DOI: http://doi.org/10.3348/jksr.2019.80.6.1241

Abstract

Although various neoplasms may develop in the ventricular system, glioblastomas are rare. An 80-year-old woman visited our hospital with intractable headache related to a right ventricular large mass, which exhibited heterogeneous enhancement involving the body, trigone, and occipital horn of the right lateral ventricle on MRI. The mass was diagnosed as glioblastoma multiforme on surgical pathology. Herein, the authors present a case and review the existing literature with regarding to incidence, pathophysiology, prognostic factors, imaging and pathologic findings of intraventricular glioblastoma multiforme.

MeSH Terms

Aged, 80 and over
Animals
Female
Glioblastoma*
Headache
Headache Disorders*
Horns
Humans
Incidence
Lateral Ventricles
Magnetic Resonance Imaging
Pathology, Surgical

Figure

• 

  Fig. 1 Intraventricular glioblastoma multiforme in an 80-year-old woman, presenting with intractable headache. A, B. CT images showing a multilobulated, large mass with heterogeneous enhancement in the right parietooccipital area. The mass extends downward along the body, trigone, and occipital horn of the ipsilateral lateral ventricle on axial (A) and coronal (B) images. C, D. Axial (C) and coronal (D) MR images reveal that the heterogeneously enhancing mass is located from the body to occipital horn of right lateral ventricle. A tentorial meningioma is found by chance (D). E. Histopathology shows nuclear polymorphism with several multinucleated giant cells and high degree of cellularity (hematoxylin-eosin staining, × 200). F. Immunohistochemical staining of the histopathology shows positive results for glial fibrillary acidic protein (× 200).

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