J Korean Neurol Assoc.  2019 Nov;37(4):403-407. 10.17340/jkna.2019.4.14.

Neuromyelitis Optica Spectrum Disorder Preceded by Myotonic Myopathy

Affiliations
  • 1Department of Neurology, Konkuk University Medical Center, Seoul, Korea. serein@kuh.ac.kr
  • 2Department of Pathology, Seoul National University Hospital, Seoul, Korea.

Abstract

Neuromyelitis optica spectrum disorder (NMOSD) is generally known as selective involvement of central nervous system. However, in recent years, some evidences have been found that NMOSD invades other peripheral organs. Especially, skeletal muscle involvement of NMOSD has been documented scantily and further studies must be required. Here, we describe a patient who first had generalized fatigue, mild weakness, and myalgia with increased level of serum creatine kinase and was finally diagnosed with myopathy associated with NMOSD.

Keyword

Neuromyelitis optica; Myopathy; Myotonia

MeSH Terms

Central Nervous System
Creatine Kinase
Fatigue
Humans
Muscle, Skeletal
Muscular Diseases
Myalgia
Myotonia
Myotonic Disorders*
Neuromyelitis Optica*
Creatine Kinase
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