J Korean Radiol Soc.  1981 Sep;17(2):302-308. 10.3348/jkrs.1981.17.2.302.

(99m)Tc-diethyl-IDA cholescintigraphy

• Kim JW
• Oh KC
• Bae BH
• Kim YS
• Park BH

• KMID: 2463408
• DOI: http://doi.org/10.3348/jkrs.1981.17.2.302

Abstract

For many years, (131)I-rose bengal has been used as the main hepatobiliary radiopharmaceutical. The undesirablephysical characteristics of the radioiodine, however, finally prevented its widespread use in clinical medicine. In recent years, a number of hepatobiliary radiopharmaceuticals employing 99mTc and 123 I as indicator have been introduced. 99mTc-diethyl-IDA is a most promising one in these agents. Cholescintigraphy, using 99mTc-diethyl-IDAwas performed in 10 normal subjects and 32 patients suffering from various hepatobiliary disturbances, from Sep. 1979 to Aug. 1980, at the departement of radiology, Maryknoll Hospital. The following results are obtained; 1. In normal fasting subjects, the liver, GB, CBD, and the proximal portion of small bowel are clearly delineated within 30 min after the injection. After a fatty meal, the radioactivity of the liver and CBD is notablydisappeared with increase of the activity in GB and small bowel. 2. A dilatation of the main biliary ducts is apathognomomic sign of partial mechanical obstructive disorders and a key point of D.Dx from hepatocellualr disorders. 3. In cases of complete biliary obstruction, the radioactivity of the liver, CBD, and small bowel isnot seperated and the backgroup activity is markedly increased. The kidneys are well visualized. 4. In severehyperbilirubinemia of above 10 mg%, this method is not valuable.

MeSH Terms

Clinical Medicine
Dilatation
Fasting
Humans
Kidney
Liver
Meals
Methods
Radioactivity
Radiopharmaceuticals
Radiopharmaceuticals