J Korean Soc Traumatol.  2019 Jun;32(2):111-114. 10.20408/jti.2018.048.

Recurrence of Minimal Change Disease Following a Motor Vehicle Trauma: An Atypical Cause and Review of Literature

• Depa J
• Coritsidis G

• KMID: 2462946
• DOI: http://doi.org/10.20408/jti.2018.048

Abstract

Minimal change disease (MCD) in children has a favorable long-term prognosis, and development of end-stage renal disease is very uncommon; less than 5%. In the first case of its kind, we report a 21-year-old female with a history of MCD at the age of 6, who had late relapse subsequent to a motorcycle accident resulting in a de-gloving skin injury and intensive care unit admission. MCD was confirmed by normal light microscopy, podocyte effacement on electron microscopy and absence of any deposits on immunofluorescence 3 weeks after the incident due to critical illness. It is postulated that the skin injury is what caused the relapse of MCD.

Keyword

Minimal change disease; Skin injury; Recurrence; Nephrology; End-stage renal disease

MeSH Terms

Child
Critical Illness
Female
Fluorescent Antibody Technique
Humans
Intensive Care Units
Kidney Failure, Chronic
Microscopy
Microscopy, Electron
Motor Vehicles*
Motorcycles
Nephrology
Nephrosis, Lipoid*
Podocytes
Prognosis
Recurrence*
Skin
Young Adult