J Korean Radiol Soc.  1985 Feb;21(1):90-95. 10.3348/jkrs.1985.21.1.90.

Quantitative Evaluation Using Histo-processing as a Complement of Conventional Hepatic Scintigraphy

• Kim CY
• Lee HG
• Yang WJ
• Bahk YW

• KMID: 2462919
• DOI: http://doi.org/10.3348/jkrs.1985.21.1.90

Abstract

The lack of specificity of an abnormal findings visualized on a conventional radiocolloid liver imaging remains a significant limitation of the examination. The purpose of this investigation is to clarify an equivocal abnormal finding visualized on a conventional liver and spleen imaging by using combination of scintiangiography and histogram as a quantiative assessment. Histo-analysis of peak colloidal distribution in the liver and spleen was undertaken as a complement of conventional liver imaging. The following useful patterns was emerged: 1. In hepatitis, the splenic uptake was slightly higher than in normal group. This change was usually not recognized in conventional imaging. 2. In liver cirrhosis, the liver uptake was markedly low whilst splenic uptake was very high, resulting in splenic shift and very low liver-spleen uptake ratio. 3. In hepatoma, the liver uptake was not definitely changed but splenic uptake was considerably high, so that the liver-spleen uptake ratio was very low. 4. In liver metastasis, both liver and splenic uptakes were within normallimits and the liver-spleen uptake ratio was not changed.

MeSH Terms

Carcinoma, Hepatocellular
Colloids
Complement System Proteins*
Evaluation Studies as Topic*
Hepatitis
Liver
Liver Cirrhosis
Neoplasm Metastasis
Radionuclide Imaging*
Sensitivity and Specificity
Spleen
Colloids
Complement System Proteins