Psychiatry Investig.  2019 Oct;16(10):715-717. 10.30773/pi.2019.07.09.1.

When Thoughts Are in a Race: Area 10 and Bipolar Disorders

Affiliations
  • 1Institute of Neuropharmacology, Kerman Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran. vsheibani2@yahoo.com

Abstract

Racing thought, when patients incessantly shift from one word or sentence to another while pending previous ones unfinished, is a symptom of (hypo)mania in bipolar disorders received less attention hitherto. Here, based on few evidence, we aim to unfold our hypothetical viewpoint that the frontopolar cortex that is believed to play a part in multitasking and management of competing goals might be dysfunctional in bipolar patients and may contribute in induction of flight of ideas. We then address new avenues for future research and try to encourage researchers to design more comprehensive studies to either accept or decline this proposed conjecture.

Keyword

Frontopolar cortex; Area 10; Bipolar disorders; Flight of ideas; Racing thought; fMRI

MeSH Terms

Bipolar Disorder*
Continental Population Groups*
Humans
Magnetic Resonance Imaging
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