Psychiatry Investig.  2014 Jul;11(3):336-339.

Dandy Walker Variant and Bipolar I Disorder with Graphomania

• Can SS
• Karakas Ugurlu G
• Cakmak S

Abstract

Cerebellum is known to play an important role in coordination and motor functions. In some resent studies it is also considered to be involved in modulation of mood, cognition and psychiatric disorders. Dandy Walker Malformation is a congenital malformation that is characterized by hypoplasia or aplasia of the cerebellar vermis, cystic dilatation of the fourth ventricle and enlargement of the posterior fossa. When the volume of posterior fossa is normal, the malformation is called Dandy Walker Variant. Case is a 32 year old male with a 12 year history of Bipolar I Disorder presented with manic and depresive symptoms, including dysphoric and depressive affect, anhedonia, suicidal thoughts and behaviours, thoughts of fear about future, overtalkativeness and graphomania, increased energy, irregular sleep, loss of appetite, increased immersion in projects, irritability, agressive behavior, impulsivity. Cranial Magnetic Resonance Imaging was compatible to the morphological features of Dandy Walker Variant.

Keyword

Dandy walker; Bipolar disorder; Cerebellum

MeSH Terms

Anhedonia
Appetite
Bipolar Disorder
Cerebellum
Cognition
Dandy-Walker Syndrome
Dilatation
Fourth Ventricle
Humans
Immersion
Impulsive Behavior
Magnetic Resonance Imaging
Male